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1、WH0WH0肺癌组织学新分类肺癌组织学新分类1 鳞状细胞癌 小细胞癌 腺癌 大细胞癌 腺鳞癌 肉瘤样癌 类癌瘤 唾液腺癌 侵袭前病变恶性上皮性肿瘤恶性上皮性肿瘤2鳞状细胞癌(Squamous cell carcinoma) 乳头状 (Papillary) 透明细胞(Clear cell) 小细胞 (Small cell) 基底样 (Basaloid) 3小细胞癌小细胞癌(Small cell carcinoma)(Small cell carcinoma) 复合性小细胞癌复合性小细胞癌(Combined small cell (Combined small cell carcinoma)car
2、cinoma) 4腺癌腺癌(Adenocarcinoma)(Adenocarcinoma) 腺癌腺癌, ,混合亚型（混合亚型（Adenocarcinoma,mixed subtypeAdenocarcinoma,mixed subtype） 腺泡性腺癌腺泡性腺癌(Acinar adenocarcinoma)(Acinar adenocarcinoma) 乳头状腺癌乳头状腺癌(Papillary adenocarcinoma)(Papillary adenocarcinoma) 细支气管肺泡癌细支气管肺泡癌(Bronchioloalveolar carcinoma)(Bronchioloalve
3、olar carcinoma) 非粘液性非粘液性(Non-mucinous)(Non-mucinous) 粘液性粘液性(Mucinous)(Mucinous) 混合性粘液性及非粘液性或未定性混合性粘液性及非粘液性或未定性(Mixed)(Mixed)5 实性腺癌伴粘液分泌实性腺癌伴粘液分泌 (Solid adenocarcinoma with mucin) (Solid adenocarcinoma with mucin) 胎儿型腺癌（胎儿型腺癌（Fetal adenocarcinomaFetal adenocarcinoma） 粘液性粘液性( (胶样胶样) )腺癌腺癌 Mucinous(Muc
4、inous(“colloidcolloid”) adenocarcinoma) adenocarcinoma 粘液性囊腺癌粘液性囊腺癌(Mucinous cystadenocarcinoma) (Mucinous cystadenocarcinoma) 印戒细胞腺癌印戒细胞腺癌(Signet ring adenocarcinoma)(Signet ring adenocarcinoma)透明细胞腺癌透明细胞腺癌(Clear cell adenocarcinoma) (Clear cell adenocarcinoma) 6大细胞癌大细胞癌(Large cell (Large cell carc
5、inoma)carcinoma) 大细胞神经内分泌癌 (Large cell neuroendocrine carcinoma) 复合性大细胞神经内分泌癌(Combined Large cell neuroendocrine carcinoma)基底样癌(Basaloid carcinoma)淋巴上皮瘤样癌(Lymphoepithelioma-like carcinoma) 透明细胞癌(Clear cell carcinoma) 大细胞癌伴横纹肌样表型 7腺鳞癌腺鳞癌腺鳞癌腺鳞癌 (Adenosquamous carcinoma)(Adenosquamous carcinoma)(Adenos
6、quamous carcinoma)(Adenosquamous carcinoma) 8肉瘤样癌肉瘤样癌肉瘤样癌肉瘤样癌（Sarcomatoid carcinomaSarcomatoid carcinomaSarcomatoid carcinomaSarcomatoid carcinoma） 多形性癌多形性癌(Pleomorphic carcinoma) (Pleomorphic carcinoma) 梭形细胞癌梭形细胞癌(Spindle cell carcinoma)(Spindle cell carcinoma) 巨细胞癌巨细胞癌(Giant cell carcinoma)(Giant
7、cell carcinoma) 癌肉瘤癌肉瘤(Carcinosarcoma)(Carcinosarcoma) 肺母细胞瘤肺母细胞瘤(Pulmonary blastoma)(Pulmonary blastoma) 9类癌瘤类癌瘤类癌瘤类癌瘤(Carcinoid tumour)(Carcinoid tumour)(Carcinoid tumour)(Carcinoid tumour) 典型类癌典型类癌典型类癌典型类癌(typical arcinoid) (typical arcinoid) (typical arcinoid) (typical arcinoid) 不典型类癌不典型类癌不典型类癌不
8、典型类癌(Atypical carcinoid)(Atypical carcinoid)(Atypical carcinoid)(Atypical carcinoid) 10唾液腺肿瘤唾液腺肿瘤唾液腺肿瘤唾液腺肿瘤(Salivary gland tumours)(Salivary gland tumours)(Salivary gland tumours)(Salivary gland tumours) 粘液表皮样癌粘液表皮样癌(Mucoepidermoid carcinoma)(Mucoepidermoid carcinoma) 腺样囊性癌腺样囊性癌(Adenoid cystic carci
9、noma)(Adenoid cystic carcinoma) 上皮上皮- -肌上皮癌肌上皮癌（Epithelial-myoepithelial carcinomaEpithelial-myoepithelial carcinoma） 11侵袭前病变侵袭前病变(Preinvasive lesions)(Preinvasive lesions) 原位鳞癌 (Squmous carcinoma in situ) 不典型腺瘤性增生 (Atypical adenomatous hyperplasia) 弥漫性特发性肺神经内分泌细胞增生 (Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia) 12 鳞状细胞癌 小细胞癌 腺癌 大细胞癌 腺鳞癌 肉瘤样癌 类癌瘤 唾液腺癌 侵袭前病变恶性上皮性肿瘤恶性上皮性肿瘤13
