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1、二甲基亚砜安全技术说明书MSDSProduct Name:Dimethyl sulfoxideSynonyms:(CH3)2SO;A 10846;a10846;Decap;Deltan;Demasorb;Demavet;DemesoCAS:67-68-5MF:C2H6OSMW:78.13EINECS:200-664-3Product Categories:Pharmaceutical Intermediates;INORGANIC & ORGANIC CHEMICALS;Organics;Analytical Chemistry;Solvents for HPLC & Spectrophoto
2、metry;Solvents for Spectrophotometry;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Dimethyl Sulfoxide (DMSO);Anhydrous Solvents;Solvent by Application;Solvent by Type;Solvents;Plastic Bottles;Analytical Reagents;Analytical Reagents for General Use;Analytical/Chromatography;C-D;Puriss
3、p.a. ACS;Solvent Bottles;Solvent Packaging Options;BRDU Cell Proliferation Assay Reagents;Cell Culture;Cell Freezing Media and Reagents;Chemical ER Chaperones;Endoplasmic Reticulum Stress;General Stem Cell Biology;Hybridoma Platform;Hybridoma Reagents;Life Science Reagents for Cell Culture;Reagents
4、and Supplements;Serum-free Media;Stem Cell Biology;Cell Biology;Cell Signaling and Neuroscience;Core Bioreagents;Cryopreservation;General Reagents;Research Essentials;Apoptosis and Cell Cycle;Life Science Reagents for Nucleic Acid Purification;Life Science Reagents for Protein Expression and Purific
5、ation;Other Apoptosis Related Reagents;Biostabilization Agents;PCR Optimization;Stabilization of Biomolecules;Biochemicals and Reagents;Life Science Reagents for PCR;Molecular Biology;PCR Reaction Components;PCR/Amplification;Plant Biotechnology;Plant Growth Regulators;Plant Tissue Culture;Primary H
6、uman Cell Culture;Specialty Media Systems;Hepatocytes;Biotech;Biotech Solvents;Life Science Reagents for Northern and Southern Blotting;Products;Returnable Containers;Sure/Seal Bottles;DMSO - Dimethyl sulfoxide;Molecular Biology Reagents;Analytical and Industrial Enzymes;and Substrates;Biochemicals;
7、Enzymes;-Glucuronidase;-Glucuronidase Drug Analysis Bundle;Inhibitors;Life Science Reagents for RNAi;Anhydrous;ACS and Reagent Grade Solvents;ACS Grade;ACS Grade Solvents;Amber Glass Bottles;Composite Drums;Drums Product Line;Semi-Bulk Solvents;VerSA-Flow Products;CHROMASOLV Plus;Chromatography Reag
8、ents &;HPLC &;HPLC Plus Grade Solvents (CHROMASOLV);HPLC/UHPLC Solvents (CHROMASOLV);NOWPak Products;UHPLC Solvents (CHROMASOLV);Universal SolventMol File:67-68-5.molDimethyl sulfoxide Chemical Propertiesmp18.4 Cbp189C(lit.)density1.100g/mLat 20Cvapor density2.7 (vs air)vapor pressure0.42 mm Hg ( 20
9、 C)FEMA3875refractive indexn20/D1.479(lit.)Fp192Fstorage temp.Store at RT.formliquid (temperature dependent)colorclear colorlessFreezingPoint18.4SensitiveHygroscopicMerck14,3259BRN506008Stability:Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong
10、 oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic.CAS DataBase Reference67-68-5(CAS DataBase Reference)NIST Chemistry ReferenceDimethyl sulfoxide
11、(67-68-5)EPA Substance Registry SystemMethane, sulfinylbis-(67-68-5)Safety InformationHazard CodesXiRisk Statements36/37/38Safety Statements24/25-37/39-26-36-23WGK Germany1RTECSPV6210000F3HS Code29309070Hazardous Substances Data67-68-5(Hazardous Substances Data)MSDS InformationProviderLanguageDimeth
12、yl sulfoxideEnglishSigmaAldrichEnglishACROSEnglishALFAEnglishDimethyl sulfoxide Usage And SynthesisChemical Propertiescolourless liquidUsageDMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectantvitrification agent for the preservation
13、of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO
14、is frequently used in the combinations with BSA or fetal bovine serum (FBS).UsageHuman and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a
15、 cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowersUsageDimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolv
