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1、The development of a discrete automatic clinical analyzerTAN Hungxue，LIU Wei。，。， GUO Qiang。，。， TANG Yuguo。Abstract：The clinical analyzer is general equipment for hospita1The discrete automatic clinical analyzer for grassroots hospital has been developed by USThis analyzer uses holographic concave gr
2、ating as spectroscopeThe wavelengthis from 340 nm to 800 nm，and its true test speed can reach 300 testshourThe analyzer is controlled by a computerIt is connected to computer through RS4 85 serial portThe Visual Basic 60 is used as program developlanguageIt is come true that computer automatically c
3、ontrols the clinical analyzerKey words：clinical analyzer；automatic control；spectrum apparatus1 Introduction Optical analysis as one of the clinical examination and analysis of the most commonly used detection methods are widely used in a variety of medical analytical instruments. Automatic biochemic
4、al analyzer is a typical application of this method. Biochemical analyzer is used for determination of human body fluids (blood, urine) in a variety of biochemical indicators (such as blood, liver function, renal function, heart function, blood glucose, lipids, minerals, etc.), analytical instrument
5、s, it can accurately quickly provide the necessary test data for doctors and chemical inspectors play an important role in clinical diagnostics and chemical testing.Automatic biochemical analyzer biochemical analytical instruments as a higher degree of automation, it biochemical analysis of the samp
6、le, add reagents, mixing, thermal reaction, detection, the results of calculation and display steps part or all of the manual referred to imitate equipment to complete, rapid processing of samples and greatly improve the accuracy and reliability of operation, reducing manual intervention, with the i
7、ncomparable advantages of the manual, has an important role in the clinical chemistry tests, hospital inspection conventional equipment.Automatic biochemical analyzer in accordance with the colorimetric approach can be divided into mobile and discrete two categories. Discrete and mobile main differe
8、nce is that control different timing and spectrophotometer. Mobile automatic biochemical analyzer cuvette Use of Mobile and its low speed of analysis, accuracy is also difficult to reach a higher level, the sample cross-contamination; discrete automatic biochemical analyzer using discrete cuvette wi
9、th each other between no crossCross contamination, the number can be placed according to the needs cuvette, the instrument accuracy and test speed can be greatly improved.Not yet completely independent research and discrete automatic biochemical analyzer, this is mainly because it involves many opti
10、cal, mechanical, electrical, calculation, liquid line, temperature control, biochemical analysis, the complexity of the system structure, control the timing demanding requirements of operational reliability and accuracy, so most of the needs of medical institutions to rely on imports. In order to br
11、eak the monopoly of foreign automatic biochemical analyzer, the Ministry of Science and Technology in 1995 and 15, has earmarked special funds for scientific and technological research, the current 15 scientific and technological research focus is to achieve the industrialization of automatic bioche
12、mical analyzer2 the basic principles “Ultraviolet and visible spectrophotometry (Ultraviolet-visible Spectrophotometry, uV-Vis)“ according to the material elements of the absorption characteristics of the UV and visible spectral regions and extent of absorption of substances qualitative and quantita
13、tive analysis of an absorption spectrometry. Analysis of the material content of the clinical examination in the blood of the automatic biochemical analyzer is the application of this method, according to the color reaction in analytical chemistry, biochemical reagents of different substances throug
14、h the shades of color reaction, Lambert Bill The law of quantitative analysis of its concentration. Lambert-Beers law expression as follows:A=lg(I。I)= bc(1)In this formula, A an absorbance; An incident radiation intensity; for a through radiation intensity; b for closing the layer thickness (cm); ab
15、sorbing compounds the molar concentration (M); is is the molar absorptivity (L mol.cm)From the above equation, the molar absorption coefficient and absorption layer thickness b is a constant, absorption of the molar concentration of c absorbance A is proportional to, can be calculated by measuring t
16、he absorbance A of the absorber of the molar concentration c. This law is widely used in UV-visible, one infrared spectral region absorption measurements, the inspection of various biochemical indicators in the automatic biochemical analyzer according to this law of.3 overall design summaryPrototype of the proposed design for the discrete automatic biochemical analyzer, as a large optical precision instruments, the prototype including the optical system, im
