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1、null8nullRANKL-RANK-OPGdhnull null null null null null null null null null null null null null null null null null null null null null null null徐岩null 综述; null 孙钦峰, null 杨丕山null 审校山东大学口腔医学院,山东济南( 250012)nullK1nullnull%y0nullbs8y08-%y0nullbs8y0- ( RANKL-RANK-OPG )dM?C %Z1oT%y0, %h?h1TbRANKL-RANK-OPGd
2、,?Cdh lM1,Mh?h,7Bhobnull1oMnullnull%y0nullbs8y08; null%y0nullbs8y0; null ; nullhnullms|nullnull R781. 4null null nullDSMnullnull Anull null nullcI|nullnull 1006- 5245( 2008) 07- 334- 03null null+M,S= ld1,?C%y0nullbs8y08-%y0nullbs8y0- ( receptor activator of nuclear factor-nullb ligand -receptor acti
3、vator of nuclear factor-nullb -osteoprogerin,RANKL-RANK-OPG)d Fya %sa1oy0bd| afd=sd,i aA1# M %hbh9 l1+%h,3RANKL- RANK-OPG FT#h?hYSB8bBaRANKL-RANK-OPGdRANKLB8OPG?C,?y0( tum or necrosis factor, TNF)8EBB,?y0M1y0( TNF- related activation- in-duced cytok ine, TRANCE)a %sy0( osteoclast d i-fferentiation f
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6、 2003, 19 ( 6): 655-660. 3 ,.3 S5, 2004, 1 ( 5): 42-45. 4 W ITTRANT Y, TH EOLEYRE S, COU ILLAUD S, et a1. E xp C ellRes, 2004, 293 ( 4): 292-301. 5 N ISH IJIMA Y, YAMAGUCH IM, KOJIMA T, et a.l O rthod C ran io-fac Res, 2006, 9( 2): 63-70. 6 TAKAYANAG IH. J PeriodontalRes, 2005, 40 ( 4): 287-293. 7 T
7、ENG Y T, NGUYEN H, GAO X, et a.l C lin Invest, 2000, 106( 6 ): R59-67. 8 RAN I C S, MACDOUGALL M. M olC ell B iolR es Comm un, 2000,3( 3 ): 145-152.null335nullb)null nullBf/,eVC ?Fn,V3 5 m in,?THem,pb7,51 /6 1 /33hi,7?ea?eaeaPZe-u.e,yN/aby3h?T.e ,$eM,Dnullenullbe+e,?,&8aaf7$?,V1beg8S_Ah,e?,B.e,S)#e0(?bNe$eB+y,MbM,M-9,v7#*8v?3|M,e$,eV -u,9Vb/ a/b,5e,aM,CeAhfM,iOe0(?,g8S_%a*%f/,In3hV?,+YVCap8H,TM$),_m,h=SD3TB),/,b(l: 2008 - 02- 25)(I nullZF)null336nullhnull 2008M7null16null7
