《抗性糊精对饱食及体重控制的作用》由会员分享，可在线阅读，更多相关《抗性糊精对饱食及体重控制的作用（21页珍藏版）》请在金锄头文库上搜索。
1、,Effectofaresistantdextrin onsatietyandweightmanagement 抗性糊精对饱食与体重控制的作用,LaetitiaDeremaux,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake食物摄入,STUDY DESIGN 研究设计,Objectives, Study description, Population, Study product administration, Groups, Parameters, Schedule description 目的、研究描述、人群、研究产品服法、
2、群组、参数、日程描述,RESULTS 结果,Satiety, Hunger feeling, Caloric & Food intake, Bodyweight, Body fat 饱食、饥饿感、热量及食物摄入、体重、体脂,CONCLUSION 结论,Bodyweight体重,Bodyfat体脂,Part I: Study Design 第一部分： 研究设计,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design,Objectives: Evaluation
3、 of the impact of a resistant dextrin on satiety, food intake and weight management 评价抗性糊精对饱食、食物摄入和体重控制的影响 Evaluation of the impact of a resistant dextrin on hunger feeling and body fat 评价抗性糊精对饥饿感及体脂的影响,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study descrip
4、tion (研究描述) Randomized, placebo-controlled, double-blind, parallel, single center 随机、安慰剂对照、双盲、平行、单中心 Implemented in China 在中国实施,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design,Population (人群) 20 healthy overweight Chinese volunteers per group (5 group
5、s 20 volunteers) 每组位健康超重中国自愿者（组自愿者） Men and women (50/50) 男性与女性（） 35 to 55 years old 35 到 55 岁 Overweight (24 BMI 28 kg/m2); Chinese cut-off points for overweight 超重（24身体质量指数28公斤米2）；中国超重切分点 Factory workers 工厂工人： working 7 days a week at Li Pu manufacturing plant 荔浦制造厂每周工作天 eating at the canteen at e
6、very meals 每餐在食堂就餐,Study design,Administration (服法) Two daily intakes of a resistant dextrin in 250ml orange juice 将抗性糊精融入250毫升橙汁，每天摄取两次 Placebo arm: Orange juice 安慰剂组： 橙汁 Treatment arms: Resistant dextrin at different dosages in orange juice 治疗组：在橙汁中加入不同剂量的抗性糊精,Study design研究设计,Satiety饱食,Hunger fee
7、ling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design,Parallel study (平行研究) Group 1: Placebo 组1： 安慰剂 Group 2: 4g resistant dextrin 2 intakes = 8g/day 组2： 4克抗性糊精 2次摄取 8克天 Group 3: 7g resistant dextrin 2 intakes = 14g/day 组3： 7克抗性糊精 2次摄取 14克天 Group 4: 9g resistant dextrin 2 intakes = 18g/day 组4：
8、 9克抗性糊精 2次摄取 18克天 Group 5: 12g resistant dextrin 2 intakes = 24g/day 组5： 12克抗性糊精 2次摄取 24克天,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design,Schedule description,Breakfast,7:00am,Lunch,12:00-12:30pm,Dinner,6:30pm,Placebo or resistant dextrin,Placebo or
9、resistant dextrin,10:00am,4:00pm,Hunger feeling questionnaire (9:50am),Hunger feeling questionnaire (3:50pm),Satiety evaluation (VAS) from 10:00am to 12:00am,Satiety evaluation (VAS) from 4:00pm to 6:00pm,Food intake evaluation,(*),(*),(*),(*),Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake
10、食物摄入,Bodyweight体重,Bodyfat体脂,Study design,Part II: Results 第二部分: 结果,Satiety 饱食 Hunger feeling 饥饿感 Food intake 食物摄入 Body weight 体重 Body fat 体脂,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Satiety evaluation by VAS 饱食评价（按视觉模拟评分法）,The resistant dextrin has a positi
11、ve and significant impact on satiety just after the first consumption at 14g, 18g and 24g/day. 在首次摄取14克、18克和24克天后，抗性糊精对饱食有积极且明显的影响。,DAY 0,Orange juice consumption,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design研究设计,Satiety饱食,Satiety evaluation by VAS 饱食评价（按视觉模拟评分法）,DAY 21,From
12、day 0 to day 21, the resistant dextrin has shown a progressive and strong impact on satiety. At day 21 and before day 21, the resistant dextrin has shown a significant modulation of satiety at 8g, 14g, 18g and 24g/day. 从首日到第21日，抗性糊精已显示出对饱食有渐进及较强的影响。在第21日及之前 ，每日摄取8克、14克。18克及24克/天，抗性糊精已显示出对饱食有明显的调节作用。
13、,Orange juice consumption,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design研究设计,Satiety饱食,Satiety evaluation by VAS 饱食评价（按视觉模拟评分法）,The effect of the resistant dextrin on satiety is time correlated and the effects are clear from day 0. 抗性糊精对饱食的作用与时间相关，且从首日开始有作用 。,Orange juice cons
14、umption,Hunger feeling饥饿感,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design研究设计,Satiety饱食,The consumption of the resistant dextrin has a positive impact on the hunger feeling score over the study period with a statistical difference from day 5. 在研究期间，使用抗性糊精饥饿感评分有正面影响，从第天起有差异。,Food intake食物摄入,Bodyw
15、eight体重,Bodyfat体脂,Study design研究设计,Satiety饱食,Hunger feeling饥饿感,Hunger feeling 饥饿感,Hunger feeling 饥饿感,The number of volunteers, who are not hungry, has increased over the study period with a dose-effect relation. 不饿的自愿者人数在研究期间增加，具有量效关系。,Food intake食物摄入,Bodyweight体重,Bodyfat体脂,Study design研究设计,Satiety饱
16、食,Hunger feeling饥饿感,Food intake 食物摄入,The resistant dextrin has shown a significant decrease in food intake at lunch over the study period, from week 3. 从第周期，抗性糊精在研究期间明显减少午餐食物摄入量,Bodyweight体重,Bodyfat体脂,Study design研究设计,Satiety饱食,Food intake食物摄入,Hunger feeling饥饿感,Body weight 体重,The resistant dextrin has shown a significant decrease in bodyweight from -0.42kg at 14g/day. This weight lost became higher with the increase of the dosage
