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1、 Enduo ,: : : Bingrong Liu, ,interdict angiogenesis,Endostatin Endostar?,Extra 9 amino acid,Endostatin,Endostar, C- XVIII, 20 kDa . Endostar N- , , EnDuo ( ) in vitro in vivo, In vitro,Control,Enduo,Endostar , ,Colon Cancer Cells (SW620, HCT-116, HT-29), In vivo,Xenograft mouse model ( in vitro),Con
2、trol,Endostar , ,Enduo, 3 - , . : Yu Bo, , , - . - 3 (3) , - . -3 , , , ., (n=250), , , , , , , Yu Bo, 2- . , 40 ( . Circulation, IF-14,4; Journal of the American College of Cardiology, IF-16,5)., ,: . .Supervisor: Prof Zhang Hong, , , ., , ,( ) , , , ,1 : ,2 : ( ),3 : ,4 : (, -, - .),5 : In vivo ,
3、,Dr Hong Zhang,Prof Hong Zhang MBBS ; MD, MS; PhD. Principal Investigator, Centre for Eye Research Australia, University of Melbourne. Deputy Head, Medical consultant of Eye Hospital, the First Clinical Hospital of Harbin Medical University. Member of Chinese Medical Association, Member of Chinese A
4、ssociation of Pathophysiology, Board Member of Corneal Group of Ophthalmology Branch of the Chinese Medical Association and Board Member of Youth Committee of Chinese Medical Association of Ophthalmology.,EnDuo , 2 : , , , EnDuo ( ) , ,In vitro : CAL-27, , (MTT assay) - (Scratch assay, ). In vivo , - ., Ganglioside - ,: : Jian Hu and Ning WangDepartment of Psychiatry in First Affiliated Hospital of Harbin Medical University and Department of Pharmacology of Harbin Medical University,17, , . . “Ganglioside” . “Ganglioside” - .,