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1、Corneal diseaseGeneralFunctions 1.cornea and sclera make up the externalwall 2.important refraction substance:+43D，3/4 of the total refractive power 3.no blood vesselImmune privilegeTransparent corneaEpitheliumBasal cellsBowman membraneStromaDescemet membraneEndotheliumKeratitisEtiology 1.infectivit
2、y : bacteria、fungi、virus、acantha amoeba 2. endogenetic: 3. spread:Pathobiology causative agent infiltration transparent corneal ulcer descemetocele corneal perforationnebulamacula corneal scar corneal fistulaleucoma Adhesiveness keratoleukomaglaucomacorneal staphylomapanophthalmitisatrophia bulbi（眼球
3、萎缩） clinical manifestationSymptom: ophthalmalgia、photophobia、tearing、spasm of eyelid、secretion、sight descentSign: ciliary congestion、corneal infiltration、corneal ulcerDiagnose Symptom + Sign laboratory examinationTherapy Remove etiological factorControl infectionPromote healingDecrease cicatricleBacterial keratitis Etiology corneal trauma pathogenic bacteria partly&systemic factors
