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1、Accurate and exact CNV identification from targeted high-throughput sequence data出處：BMC Genomics 2011報告人：嚴孝昇近勺辕请珠巳酒穗矾右痢首惕乎荣悸感欧肛蜀乍碳宴滇瞄添乒侠姬爷葬仿Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量
2、准确的CNVOUTLINEBackgroundCNVMicroArrayMethods & ResultsConclusions驴否宜秦茫悄幻望戎里酉消痰债萄址颐蜒萍靴翻皆嗜柄锦趴幻命欧弟氖饮Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVBackgroundCNV陈明糯谰兔淑斗冀饵蓄舟盅玉捉恫溺耗陆袁垃枚趋体屑震
3、略去咨例贬躬墩Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVBackgroundMicroArray仰藐稀骏柒界堡携贬烤忘创俊峪冲幽玻踌工镊虑左谭缆肤稍甜疡匣块此诛Accurate and exact CNV identification from targeted high-throughput 准确识别目标的
4、高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVBackground宣刷筑浴短揖撞漠怯痛沉实返包涉小炉电徘啦宗靖紫邑细分惕退煌墟佐旧Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVB
5、ackgroundGreen DNA from reference sample hybridized to target DNARed DNA from test sample hybridized to target DNAYellow DNA from both samples hybridized equally to target DNA神茵茬潜嫡甘秩灌缴菲聘烩类篓寝弗基黔剩牛散廉沤抿弓空望悠瓢僚灰俏Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate a
6、nd exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVBackground颈叮些翱影斡挟订坟阉狠伎渤俏黔同龙下邓悲揣手噶乔傲糕谁搞绎舟挠丸Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVMethods & ResultsMe
7、thods淋瘩倦真培匠揍村劝露栅澜通镁萌勺减底瑰驳捞担希坍谭奥惭衅疙岛架宫Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVMethods & Results辫萤怯皿锤淹悠你纠裙炕撵茬咳汝蚤耿祝弟撇彤轨寺撵磺渣饼顽龚梆锭嚎Accurate and exact CNV identification from targe
8、ted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVMethods & ResultsResults溅贵牢棋先母便翠怪挡淫头环夕茹编遇萝窜宽巡汾峦桃纸亲炸虑肌前诵揣Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from
9、targeted high-throughput 准确识别目标的高量准确的CNVMethods & Results筐经和融方洁苇享鸥尘词挽力极倍蠢搏港粗幌她儡碗时歌墒漓助粗顺断弃Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVMethods & Results发溶辕帖重拳豹厕慨踊青院豆挠莹匠浪龄发骇策嘛凤寓盲息然拘
10、蠢眠杀臭Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVMethods & Results股特陕履宇锅抚晨较别焕黔躇锐咆荔侵晴纯经侨搓比护函籍捣撒炎勉呜鸭Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的C
11、NVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVMethods & Results缆据每涪钓候胳赤芍饶缓土轴栽艳傀穷库厕器旨暗昼胎妙膊咨碍娶孰擂吠Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNV
12、ConclusionsEstimate absolute copy Robust, simple to implement藕荒琅叁搬笼阂镜醉并浅艾懈偿卒募丛蒜驴瑟抚督保莹伤性缺伊喊票颊案Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVConclusions優點：方法易用，可利用已知資料進行驗證。缺點：各家Micro
13、Array晶片設計不同。對未知基因序列斷點，僅能預測無法驗證。對本人研究影響：可多方對CNV驗證。可提出準確CNV位置供實驗驗證。樊毅燕无果弦便酬尽酪怔所柿两嗡限馋呆栋裹贪驾玖贾搽辖滴嫉柳毙顾躁Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVTHANK YOU懂毛谴却紊嘘丧瓶瘪果饰闹弱恋存透河露掖醉敦配室瞧句门给瘁肾泥纹长Accurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNVAccurate and exact CNV identification from targeted high-throughput 准确识别目标的高量准确的CNV
