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1、第三节弧菌VIBRIO种类霍舌1弧菌 vibrio cholerae副溶血性弧菌 Vibrio parahaemolyticus学习要点* 1 .掌握分类，致病物质，致病机理。* 2.霍乱粪便的特征3.熟悉形态、染色、动力、培养（耐碱性），防治原则。一、霍乱弧菌霍乱cholera所致霍乱为烈性传染病，被列为国境检疫的传染病（一）两生物型：古典生物型 classical biotypeELTOR生物型：目前主要病原菌（二）生物学性状1、形态新分离菌弧状，一条鞭毛，逗点状，运动极活泼，似鱼群”穿梭（三）传染方式粪-口途径 fecal contamination10 7-10 9弧菌/ml粪便主要的
2、动物传染源：海产品（贝壳类）Ingestion of these without adequate cooking can transmit the disease我国生食、半生食所致霍乱占饮食感染的80%泥纵、鳍鱼是保存宿主（四）发病机理：霍乱症状水样腹泻 watery diarrhea（no red blood cells and white blood cell, painless） 呕吐vomit排泄米汽水样便 Rice-water stool体液平衡失调休克shock（五）微生物学检查与预防?取米泪水样粪便或呕吐物为标本?特异性预防：接种霍乱死疫苗小结1、分类：古典生物型ELTor
3、生物型2、致病物质：菌毛、鞭毛、粘多糖酶，霍乱肠毒素enterotoxinSummery from WHOCholera is an acute intestinal infection caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae.It has a short incubation period, from less than one day to five days, and produces an enterotoxin that causes a copious, painless, watery diarrhoea that can quickly lead to severe dehydration and death if treatment is not promptly given. Vomiting also occurs in most patients
