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1、尿路感染 Urinary tract infection,UTI,Definition,尿路感染是指尿路内大量微生物繁殖而引起的尿路炎症,可有或无临床症状。 Urinary tract infection refers to the urinary tract inflammation caused by a large number of pathogenic microorganisms multiply within the urinary tract , with or without clinical symptoms.,Urinary tract 尿路,肾脏,输尿管,膀胱,尿道,C
2、lassification,上 尿 路 感 染Upper UTI下 尿 路 感 染Lower UTI,Based on the position,肾盂肾炎 pyelonephritis pailunifraitis输尿管炎 ureteritis juretraitis膀胱炎 cystitis sistaitis尿道炎 urethritis juriraitis,肾盂肾炎pyelonephritis 输尿管炎ureteritis,膀胱炎cystitis尿道炎urethritis,Classification,According to pathogens,细菌性尿感Bacterial UTI真菌性
3、尿感Fungal UTI,common,病原菌种类,病因,细菌感染:Bacterial infection 真菌 病毒 原虫,革兰阴性杆菌 Gram-negative bacteria(95%),大肠杆菌 70% escherichia coli ( E.coli ) 副大肠杆菌、变形杆菌、 产碱杆菌、产气杆菌、 绿脓杆菌,Defense mechanism 防御机制,尿路通畅时尿液能冲走绝大部分细菌Urine can wash away the majority of bacteria尿路粘膜可分泌IgG、IgAUrinary tract mucosa secrete IgG, IgA尿液含
4、高浓度尿酸和有机酸,pH值低Urine contain high levels of uric acid and organic acid, Low pH value男性排尿时前列腺液有杀菌作用Prostatic secretion have germicidal effect,Invading path 感染途径,上行感染 (90%):一侧或双肾病变Ascending infection血行感染:双肾病变Bloodstream infection(rare),严重尿路阻塞Severe urinary tract obstruction 机体免疫力低下 Low immunity,Ascendi
5、ng infection,肾输尿管膀胱尿道,Predisposing factors 易感因素,女性 female尿流不畅或尿液返流Poor urine、urine reflux使用尿道插入性器械Using urethral insertion device机体抵抗力低下Low immunity尿道口周围或盆腔炎症inflammation,female accounts for the majority,女性尿道短而直 urethra is short and straight女性尿道与阴道、肛门邻近 urethra is near the vagina and anus 经期menstruation性生活sex妊娠期pregnancy等,Thank you!,