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1、ISHIB 2007 Innovating Vascular Health: Practical Applications to Clinical Practice,Critical Challenges in Cardiovascular Disease,Program Chairwoman Shawna D. Nesbitt, MD, MS Associate Professor Department of Internal Medicine Division of Hypertension University of Southwestern Texas Medical School D
2、allas, TX,CME-accredited symposium jointly sponsored by the American Society of Hypertension and CMEducation Resources, LLC Commercial Support: Sponsored by an independent educational grant from Novartis Pharmaceuticals Mission statement: Improve patient care through evidence-based education, expert
3、 analysis, and case study-based management Processes: Strives for fair balance, clinical relevance, on-label indications for agents discussed, and emerging evidence and information from recent studies COI: Full faculty disclosures provided in syllabus and at the beginning of the program,Welcome and
4、Program Overview,Program Educational Objectives,As a result of this session, physicians will be able to:Identify the importance of early treatment of patients with high blood pressure, and the importance of treating both systolic and diastolic blood pressure abnormalities.Implement clinical strategi
5、es that help patients achieve blood pressure goals as quickly as possible, using combination therapy, when indicated.Identify prescribing strategies that reduce side effects and increase the likelihood of adherence to an antihypertensive drug regimen.Characterize and distinguish among safety profile
6、s of and efficacy characteristics of antihypertensive agents used in the African American population.,Program Educational Objectives,Recognize markers of target organ damage and learn which antihypertensive agents are useful for preventing end organ complications such as CV disease and diabetic rena
7、l disease.Manage hypertension as a systematic disease, with multiple manifestations, and associations, including metabolic syndrome and associated risk factors.Address complications linked to healthcare disparities observed in specific patient populations, and the importance of providing access, tre
8、atment, and monitoring of patients with multiple risk CV risk factors.Manage African American patients with features of the metabolic syndrome, and its implications for multiple risk factor management,Program Faculty,Program Chairwoman Shawna D. Nesbitt, MD, MS Associate Professor Department of Inte
9、rnal Medicine Division of Hypertension University of Southwestern Texas Medical School Dallas, TexasKen Jamerson, MD Professor of Medicine Cardiovascular Medicine University of Michigan Health System Ann Arbor, Michigan,Jackson T. Wright, Jr., MD, PhD, FACP Professor of Medicine Program Director, Ge
10、neral Clinical Research Center Case Western Reserve University Director, Clinical Hypertension Program University Hospitals of Cleveland Chief, Case Western Reserve University Hypertension Section(Louis Stokes VAMC) Cleveland, Ohio,Program Agenda,8:00 8:25 PM HypertensionA Systemic Disease Requiring
11、 Systematic Approaches to Therapy: Recent Clinical Practice Recommendations Focusing on Combination Therapy in Difficult-to-Treat Patient Populations with High Blood Pressure and Compelling ConditionsJackson T. Wright, Jr., MD, PhD, FACP 8:25 8:55 PM The Evolving Landscape of Antihypertensive Therap
12、y: Direct Renin Inhibition, Combination Therapy, and Implications for African American and Other Ethnic Populations Shawna D. Nesbitt, MD, MS8:55 PM Questions and Interactions with the Faculty,The Current Landscape of Cardiovascular Risk Management in African Americans Where Co-morbidity Matters The
13、 Evolving Relationship Between Risk Factors, Diabetes, Hypertension, And Vascular Complications,Shawna D. Nesbitt MD, MS Associate Professor of Internal Medicine University of Texas Southwestern Dallas, Texas,Introduction and Overview,Changing TrendsHispanics are the fastest-growing segment of the p
14、opulation, and now account for 13% U.S., as do African Americans.The U.S. Asian population currently consists of 10.6 million people, and represents 4% U.S.,; however, this population group is expected to triple in size by 2050.,The U.S. Population is Becoming Increasingly Diverse,Adapted from U.S.
15、Census Bureau, 2004. Table 1a. Accessed Dec. 1, 2006.,Southern U.S. Has the Highest Concentration of African-Americans,25.0 to 60.0 12.3 to 24.9 5.0 to 12.2 0.3 to 4.9,People indicating exactly one race, Black or African American, as a percent of total population by state,Adapted from U.S. Census Bu
16、reau, 2002 Redistricting Data (PL 94-171) Summary File,Estimated Rates of US Adults With Hypertension by Sex, Race, and Ethnicity NHANES 1988-1994 to 1999-2000,Fields et al. Hypertension. 2004;44:398-404. Hajjar and Kotchen. JAMA. 2003;290:199206,All,Mexican American,Non-Hispanic White,Hypertensive Adults (Rate, Percent SE),45,30,20,15,0,10,25,40,5,1999-2000,1988-1994,F,M,F,M,35,Hypertension Treatment and Control Rates by Race/Ethnicity: NHANES 2000,