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1、人从作用机理看晓期乳腔痛内公泌治疗策略仁国业人雌激素受体结构及作用机理|内分泌药物作用机制语期乳腺癌内分泌治疗策略夸雍二醇Regulateathrough4E2-regulatedlPhospMorylatonapalchange沥兄|iStructureHSPa0一丨a1CKodenesiaenwmalolcaeweoogBs882PoecSoimijpreseniedalFlhesiantS0onglaucinastgiStanohaco峰激素受体结构及作用机理内分泌药物作用机制/鳢期乳腺癌内分泌冶疗篝略加忆w1CKkOdenesalsJnumaolcaescooggrasts5GnRH激
2、动剂(_与区屹仪他莉首苏2RsSoimidpresenidalflhesantUonglacimastoiiStiahazot基因转录Ec国ftf团018喵国诊3闵AntonyHoweletalCANCER200089(1817825J氟维司群:新型雌激素受体下调剂FaslodexFaslodexistheonyEThattargets,bndsto,blocksanddeoradestheEmakingitamorepolentinhibioroftheERpathwaythanAlsandamoxien;WomenwithABCivelongerwhenteatedWihFaslodex500mg,comparedtootherET;TheFaslodex500mgsunivalbeneftisachievedwitnout9Xp手u瞻tochemoiketoxiciyordetimenttopatentQOL氟维晕睢一_结合、阻断并东降解ER的内分泌药物精准靳向雕激索受体结合梅解ER受体JoimFRobetsonetalCANCERPESEARCH51,6738-6746ToyW.elalNalGeret2013Dec45(121H43845.
