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1、Yang Yu (俞洋俞洋), PhD 非编码核酸院重点实验室非编码核酸院重点实验室 中国科学院生物物理研究中国科学院生物物理研究所所 手机：手机：1302006494113020064941 Datun Road 15, Chaoyang District Beijing, China 100101 Date of Preparation: Nov 11th, 2016 Research Experience: 10/2016 Present Principle Investigator, Key Laboratory of Non-coding RNA, Institute of Bio
2、physics, Chinese Academy of Sciences, China 03/2010 09/2016 Dr. Gregory Hannons Lab, Cold Spring Harbor Laboratory Postdoctoral Research Fellow 09/2007 02/2010 Dr. Timothy W. Nilsens Lab, Case Western Reserve University Postdoctoral Research Associate 08/2002 08/2007 Dr. Timothy W. Nilsens Lab, Case
3、 Western Reserve University Graduate Student Research Assistant 06/2000 06/2002 Dr. Yi Zhangs Lab, Wuhan University Undergraduate Research Assistant Education: 07/2002 08/2007 Case Western Reserve University PhD. Biochemistry, Advisor: Dr. Timothy W. Nilsen Cleveland, OH 09/1998 06/2002 Wuhan Univer
4、sity BS. Virology Wuhan, China Publications: Yu Y., Gu J., Jin Y., Luo Y., Preall J., Ma J., Cezch B. and Hannon G.J. (2015) Panoramix enforces piRNA-dependent co-transcriptional silencing. Science, 350 (6258): 339-342. Vagin, V.*, Yu Y.*, Jankowska A.*, Luo Y., Malone C.D., Harrison E., Rosebrock A
5、., Wakimoto B.T., Fagegaltier D., Muerdter F. and Hannon G.J. (2013) Minotaur is critical for primary piRNA biogenesis. RNA, 19(8): 1064-77. (* equal contribution). Muerdter F., Guzzardo P.M., Gillis J., Luo Y., Yu Y., Chen C., Fekete R. and Hannon G.J. (2013) A genome-wide RNAi screen draws a genet
6、ic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell, 50(5): 736-748. Yu Y., Maroney P.A., Denker J.A., Zhang X.H., Dybkov O., Luhrmann R., Jankowsky E., Chasin L.A. and Nilsen T.W. (2008). Dynamic regulation of alternative splicing by silencers that modulate 5 sp
7、lice site competition. Cell, 135(7): 1224-36. Maroney P.A., Yu Y., Fisher J. and Nilsen T.W. (2006). Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol. 13(12):1102-7. Maroney P.A., Yu Y. and Nilsen T.W. (2006). MicroRNAs, mRNAs, and translatio
8、n. Cold Spring Harbor Symposium Quantitative Biol. 71:531-5. Book Chapters: Yu Y. and Nilsen T.W. (2009). Mechanisms by which microRNAs regulate gene expression in animal cells. In Regulation of Gene Expression by Small RNAs. Gaur R.K. and Rossi J.J. Eds. CRC Press. Awards and Honors: Travel Award f
9、rom Mobile Genetic Elements, Woods hole, MA, September 2015. Best Poster Award at CSH-Asia Conference: RNA Biology. Suzhou, China, October, 2012. American Heart Association Postdoctoral Fellowship Award. July 2009 to June 2011. Travel Award for Eukaryotic mRNA Processing meeting at Cold Spring Harbo
10、r. August, 2009. The Young Scientist Program Fellowship, 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology: “Biomolecules for Quality of Life”, Shanghai, China. July, 2009. Keystone Symposia Scholarship, Keystone Meeting on The Biology of RNA Silencing at Victor
11、ia, British Columbia, Canada. April, 2009. Conference Presentations and Abstracts: Panoramix enforces piRNA-dependent co-transcriptional silencing. The Non-Coding Genome, EMBL symposium, Heidelberg, Germany, 2015 (Oral presentation) Panoramix enforces piRNA-dependent co-transcriptional silencing. Mo
12、bile Genetic Elements: In Silico, In Vitro, In Vivo, Woods Hole, MA, 2015 (Poster) Panoramix enforces piRNA-dependent co-transcriptional silencing. 80th Symposium: 21st Century Genetics - Genes At Work, Cold Spring Harbor, NY, 2015 (Poster) Panoramix enforces Piwi-mediated co-transcriptional silenci
13、ng. NIH Symposium “RNA Biology 2015“, Bethesta, MD, 2015 (Poster) Obelix is a licensing factor for Piwi-mediated co-transcriptional silencing. CSH-Asia Conference: RNA Biology. Suzhou, China, 2014. (Oral presentation) Minotaur is critical for primary piRNA biogenesis. Cold Spring Harbor meeting on R
14、egulatory and non-coding RNAs, Cold Spring Harbor, NY, 2014. (Poster) Minotaur is critical for primary piRNA biogenesis. Keystone Meeting on RNA Silencing, Seattle, Washington, 2014. (Poster) Minotaur is critical for primary piRNA biogenesis. Ninth Cold Spring Harbor meeting on Eukaryotic mRNA Proce
15、ssing, Cold Spring Harbor, NY, 2013. (Oral presentation) Minotaur is critical for primary piRNA biogenesis. CSH-Asia Conference: RNA Biology. Suzhou, China, 2012. (Poster) EMS screen revealed a functional link between phosphatidic acid and protein phosphatase 1 in primary piRNA pathway. Cell Symposi
16、um on Regulatory RNAs. Chicago, IL, 2011. (Poster) Enhanced magnitude of miRNA-mediated regulation upon muscle differentiation. Seventh Cold Spring Harbor meeting on Eukaryotic mRNA Processing, Cold Spring Harbor, NY, 2009. (Oral presentation) Enhanced magnitude of miRNA-mediated regulation upon muscle differentiation. Rustbelt RNA meeting, Mount Sterling, Ohio, 2009. (Oral presentat
