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1、Captain 256 germson *9The Case of the Disappearing FingerprintsOne useful anti-cancer drug can effectively erase the whorls and other characteristic marks that give people their distinctive fingerprints. Losing _1 them could become troublesome. A case released online in a letter by Annals of Oncolog
2、y indicates how big a _2 problem _ of losing fingerprints is.Eng-Huat Tan, a Singapore-based medical doctor describes a 62-year old man who has used capecitabine to _3 treat _ his nasopharyngeal cancer. After three years on the _4 drug._ ,the patient decided to visit U. S. relatives last December. B
3、ut he was stopped by U. S. customs officials _ 5for _ 4 hours after entering the country when those officials couldnt get fingerprints from the man. There were no distinctive swirly _6 marks _ appearing from his index finger.U. S. customs has been fingerprinting incoming foreign visitors for years,
4、Tan says. Their index fingers are _7 printed._ and screened against digital files of the fingerprints of bad guys terrorists and potential criminals that our federal guardians have been tasked with keeping out of the country. Unfortunately, for the Singaporean traveler,one potential _8 side _ effect
5、 of his drug treatment is a smoothing of the tissue on the finger pads. _9 Hence _ ,no fingerprints.“It is uncertain when fingerprint loss will _10 begin _ to take place in patients who are taking capecitabine,” Tan points out. So he cautions any physicians who _11 prescribe _ the drug to provide th
6、eir patients with .a doctors note pointing out that their medicine may cause fingerprints to disappear.“Eventually, the Singapore traveler made it into the United States. I guess the name on his passport didnt raise any red flags. But he,s also now got the explanatory doctors note and wont leave hom
7、e _12without_ it.By the way, maybe the Food and Drug Administration, _13which_ approved use of the drug 11 years ago, should consider _14_ updating _ its list of side effects associated with this medicine. The current list does note that patients may experience vomiting, stomach pain and some other
8、side effects. But no where _15 does._ it mention the potential for loss of fingerprints.*6Once-daily Pill Could Simplify HIV TreatmentBristol-Myers Squibb and Gilead Sciences have combined many HIV drugs into a single pill Sometimes the best medicine is more than one kind of medicine. Malaria, tuber
9、culosis and HIV/AIDS,2 for example, are all treated with combinations of drugs. But that can mean a lot of pills to take. It would be simpler if drug companies combined all the medicines into a single pill, taken just once a day. Now, two companies say they have done that for people just starting tr
10、eatment for HIV, the virus that causes AIDS. The companies are Bristol-Myers Squibb and Gilead Sciences. They have developed a single pill that combines three drugs currently on the market.3 Bristol-Myers Squibb sells one of them under the name of Sustiva.4 Gilead combined the others, Emtriva and Vi
11、read, into a single pill in two thousand four. Combining drugs involves more than technical issues. It also involves issues of competition if the drugs are made by different companies. The new once-daily pill is the result of what is described as the first joint venture agreement of its kind in the
12、treatment of HIV In January the New England Journal of Medicine5 published a study of the new pill. Researchers compared its effectiveness to6 that of the widely used combination of Sustiva and Combivir. Combivir contains two drugs, AZT7 and 3TC.8 The researchers say that after one year of treatment
13、, the new pill suppressed HIV levels in more patients and with fewer side effects.9 Gilead paid for the study. Professor Joel Gallant at the Johns Hopkins School of Medicine in Baltimore, Maryland, led the research. He is a paid adviser to Gilead and Bristol-Meyers Squibb as well as the maker of Com
14、bivir, GlaxoSmithKline. Glaxo Smith Kline reacted to the findings by saying that a single study is of limited value. It says the effectiveness of Combivir has been shown in each of more than fifty studies. The price of the new once-daily pill has not been announced. But Gilead and Bristol-Myers Squi
15、bb say they will provide it at reduced cost to developing countries. They plan in the next few months to ask the United States Food and Drug Administration10 to approve the new pill. There are limits to who could take it because of the different drugs it contains. For example, pregnant women are tol
16、d not to take Sustiva because of the risk of birth disorders.11 Experts say more than forty million people around the world are living with HIV*7Exercise Whether or not exercise adds to the length of life, it is common experience that a certain amount of regular exercise improves Captain 256 germson the health and contributes a feeling of well-being. Fu