大脑镰下疝致皮质脊髓束损伤患者的神经功能重塑

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1、SICENCE 新闻发布 作者:Jeong Pyo Seo 稿号:NRR-148-14大脑镰下疝致皮质脊髓束损伤患者的神经功能重塑弥散张量纤维束成像技术的发展使 3 种运动神经纤维束,即皮质脊髓束、红核脊髓束、皮质网状束的三维重建和评估成为可能。皮质脊髓束是负责人类大脑运动功能的最主要神经纤维束,已有研究报道了小脑幕切迹疝皮质脊髓束损伤及其恢复情况,但大脑镰下疝皮质脊髓束损伤及其恢复的报道则几乎未见。来自韩国岭南大学医学院的 Sung Ho Jang 教授领导的团队,应用弥散张量纤维束成像对 1 例 53 岁男性右侧额顶颞叶硬膜下血肿、大脑镰下疝患者皮质脊髓束变化进行检查。患者入院后行开颅减压

2、,清除血肿治疗,并于发病 6 周后进行康复干预。发病后 7 个月,患者肢体功能基本恢复正常。6 周时的弥散张量纤维束成像显示,双侧皮质脊髓束的大脑皮质至皮质下白质段变细;发病后 7 个月时的弥散张量纤维束成像显示,前述变细皮质脊髓束段增厚。皮质脊髓束的这种恢复性变化,可能是大脑镰下疝患者经康复干预致神经功能重塑的结果。文章发表在中国神经再生研究(英文版) 杂志 2014 年 6 月第 12 期。Article: Recovery of the corticospinal tracts injured by subfalcine herniation: a diffusion tensor tr

3、actography study by Jeong Pyo Seo, Sung Ho Jang (Department of Radiology, Second Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Daegu, Republic of Korea)Seo JP, Jang SH. Recovery of the corticospinal tracts injured by subfalcine herniation: a dif

4、fusion tensor tractography study. Neural Regen Res. 2014;9(12):1231-1233. 欲获更多资讯:Neural Regen ResNeurologic recovery from corticospinal tract injury due to subfalcine herniationSICENCE 新闻发布 作者:Jeong Pyo Seo 稿号:NRR-148-14After development of diffusion tensor tractography (DTT), which is derived from

5、diffusion tensor imaging (DTI), three-dimensional reconstruction and estimation for three motor tracts, such as the corticospinal tract, the rubrospinal tract, and the corticoreticular pathway became possible. The corticospinal tract is known to be a major neural tract for motor function in the huma

6、n brain. Several studies have reported on injury of the corticospinal tract by transtentorial herniation. In addition, some studies have demonstrated recovery of a corticospinal tract injured by transtentorial herniation. However, very little is known about injury and recovery of the corticospinal t

7、ract related to subfalcine herniation. Researchers at College of Medicine, Yeungnam University, Republic of Korea, led by Prof. Sung Ho Jang report on a 53-year-old, male patient with subdural hematoma in the right fronto-parietal-temporal lobe and subfalcine herniation patient who showed recovery o

8、f the corticospinal tract, which was injured by the effect of a subfalcine herniation, using DTT. The patient underwent decompressive craniectomy and removal of a hematoma at admission. At 6 weeks after onset, he was transferred to the rehabilitation department for rehabilitation. His weakness was r

9、ecovered to a nearly normal state at 7 months after onset. DTT results showed that both corticospinal tracts were narrowed from the cerebral cortex to the subcorical white matter at 6 weeks after onset; however, thickenings of narrowed portions of both corticospinal tracts on 7-month DTT appear to i

10、ndicate recovery of the injured corticospinal tracts. The recovery of the injured corticospinal tracts induced by subfalcine herniation may be a result of neurological remodeling under rehabilitation intervention. This article is released on the Neural Regeneration Research (Vol. 9, No. 12, 2014).Ar

11、ticle: Recovery of the corticospinal tracts injured by subfalcine herniation: a diffusion tensor tractography study by Jeong Pyo Seo, Sung Ho Jang (Department of Radiology, Second Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Daegu, Republic of Korea)Seo JP, Jang SH. Recovery of the corticospinal tracts injured by subfalcine herniation: a diffusion tensor tractography study. Neural Regen Res. 2014;9(12):1231-1233.

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