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1、A NEW LOOK AT HYPOTHYROIDISM Edited by Drahomira Springer A New Look at Hypothyroidism Edited by Drahomira Springer Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allo
2、ws users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to re
3、publish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build up
4、on published chapters even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessa
5、rily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas c
6、ontained in the book. Publishing Process Manager Igor Babic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February, 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from ordersintechweb.org A New
7、 Look at Hypothyroidism, Edited by Drahomira Springer p. cm. ISBN 978-953-51-0020-1 Contents Preface IX Part 1 Introduction 1 Chapter 1 Hypothyroidism 3 Osama M. Ahmed and R. G. Ahmed Chapter 2 Environmental Thyroid Disruptors and Human Endocrine Health 21 Francesco Massart, Pietro Ferrara and Giuse
8、ppe Saggese Part 2 Autoimmune Thyroid Diseases 45 Chapter 3 Hashimotos Thyroiditis 47 Arvin Parvathaneni, Daniel Fischman and Pramil Cheriyath Chapter 4 Hashimotos Disease 69 Noura Bougacha-Elleuch, Mouna Mnif-Feki, Nadia Charfi-Sellami, Mohamed Abid and Hammadi Ayadi Chapter 5 Hashimotos Disease -
9、Involvement of Cytokine Network and Role of Oxidative Stress in the Severity of Hashimotos Thyroiditis 91 Julieta Gerenova, Irena Manolova and Veselina Gadjeva Chapter 6 Different Faces of Chronic Autoimmune Thyroiditis in Childhood and Adolescence 125 Ljiljana Saranac and Hristina Stamenkovic Part
10、3 Pregnancy and Childhood 133 Chapter 7 Treatment of Graves Disease During Pregnancy 135 Teresa M. Bailey VI Contents Chapter 8 Universal Screening for Thyroid Disorders in Pregnancy: Experience of the Czech Republic 147 Eliska Potlukova, Jan Jiskra, Zdenek Telicka, Drahomira Springer and Zdenka Lim
11、anova Chapter 9 Thyroid Function Following Treatment of Childhood Acute Lymphoblastic Leukemia 159 Elpis Vlachopapadopoulou, Vassilios Papadakis, Georgia Avgerinou and Sophia Polychronopoulou Chapter 10 Congenital Hypothyroidism and Thyroid Cancer 175 Minjing Zou and Yufei Shi Chapter 11 Hypothyroid
12、ism and Thyroid Function Alterations During the Neonatal Period 191 Susana Ares, Jos Quero, Beln Senz-Rico de Santiago and Gabriela Morreale de Escobar Chapter 12 Neonatal-Prepubertal Hypothyroidism on Postnatal Testis Development 209 S.M.L. Chamindrani Mendis-Handagama Chapter 13 Congenital Hypothy
13、roidism due to Thyroid Dysgenesis: From Epidemiology to Molecular Mechanisms 229 Johnny Deladoey Chapter 14 Consideration of Congenital Hypothyroidism as the Possible Cause of Autism 243 Xiaobin Xu, Hirohiko Kanai, Masanori Ookubo, Satoru Suzuki, Nobumasa Kato andMiyuki Sadamatsu Preface This book p
14、rovides both the basic and the most up-to-date information on the clinical aspect of hypothyroidism. This first part offers general and elaborated view on the basic diagnoses in overt and subclinical hypothyroidism, autoimmune thyroid diseases and congenital hypothyroidism. Researchers and clinician
15、s experts provide results of their long time experience and results of their own scientific work. This information may be helpful for all of physician not only endocrine specialization. Introductory chapters summarize the basic theory of hypothyroidism; following chapters describe Hashimotos disease
16、 and congenital hypothyroidism - the formation, the indication and the treatment. This first part contains many important specifications and innovations for endocrine practice. I would like to thank all of authors who had helped in the preparation of this book. We hope it would be useful as a current resource for endocrine specialists. Drahomira Springer Institute of Clinical Biochemistry and Laborat
