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1、大数据与SCI论文写作ICU大数据指的是所涉及的数据量规模巨大到无法通过人工，在合理时间内达到截取、管理、处理、并整理成为人类所能解读的信息。“大数据”时代已经降临，在商业、经济及其他领域中，决策将日益基于数据和分析而作出，而并非基于经验和直觉。-2012纽约时报Data-drivendecisionmakingLeoAnthonyCeli,RogerG.Mark,DavidJ.Stone,andRobertA.Montgomery“BigData”intheIntensiveCareUnit.ClosingtheDataLoop,AmericanJournalofRespiratoryand
2、CriticalCareMedicine,Vol.187,No.11(2013),pp.1157-1160.ElysiumBigdata-criticalcareWhyusedatabase?efficientuseofresearchinvestments.UnethicalGreatergeneralizability(largeregistriesandadministrativedata)Primarydatacollectionistooonerous(5-or10-yrfollow-ups)morepreciseestimateofeffect(largesample)Exampl
3、es Data SourcesSELECTING A DATA SOURCEData QualityTaxonomy of the QuestionMapping the Question to the DataData QualityBlackN,PayneM:Directoryofclinicaldatabases:Improvingandpromotingtheiruse.QualSafHealthCare2003;12:348352Taxonomy of the QuestionMyexperiencewithMIMIC-2publicresearcharchiveofdatacoll
4、ectedfrompatientsinintensivecareunits（30000）Openaccess,freelyavailiable(http:/physionet.org/mimic2/)HighresolutionBethIsraelDeaconessMedicalCenter(Boston)TechnologyprovidedbyMIT.Latestversion:2001-2008AccesstoMIMIC-2Figure 1. Relationship between initial iCa (upper panel) and logit transformed morta
5、lity by using Lowess smoothing technique.ZhangZ,XuX,NiH,DengH(2014)PredictiveValueofIonizedCalciuminCriticallyIllPatients:AnAnalysisofaLargeClinicalDatabaseMIMICII.PLoSONE9(4):e95204.doi:10.1371/journal.pone.0095204http:/www.plosone.org/article/info:doi/10.1371/journal.pone.0095204Table 3. Multivari
6、able logistic regression categorizing calcium values into intervals by using linear spline function.ZhangZ,XuX,NiH,DengH(2014)PredictiveValueofIonizedCalciuminCriticallyIllPatients:AnAnalysisofaLargeClinicalDatabaseMIMICII.PLoSONE9(4):e95204.doi:10.1371/journal.pone.0095204http:/www.plosone.org/arti
7、cle/info:doi/10.1371/journal.pone.0095204Table 4. Multivariable logistic regression categorizing calcium values into design variables.ZhangZ,XuX,NiH,DengH(2014)PredictiveValueofIonizedCalciuminCriticallyIllPatients:AnAnalysisofaLargeClinicalDatabaseMIMICII.PLoSONE9(4):e95204.doi:10.1371/journal.pone
8、.0095204http:/www.plosone.org/article/info:doi/10.1371/journal.pone.0095204DatamanagementLongformatidyearsexincue-180050000181055001182060000280120001281122000282133000380030000381020000382010001Wideformatidsexinc80inc81inc82ue80ue81ue82-105000550060000102120002200330010030300020001000001MissingvaluesMultipleimputationtechniqueInmyhospital海泰电子病历系统SQL语言集合（http:/
