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ABCDE Structured Approach for Weaning FailureIntroductionApproach for weaningParameters / indicationsTrialsWeaning failureNo pass a SBTReintubation 48 hrs post-extubationFocusWeaning “ABCDE”AirwayBrainCardiacDiaphragmendocrineAirway/lungResistance of upper airwayTracheal obstruction more than 4 weeks on MVThe work of breathing increases post extubation more 5.5 ds on MVCOPDPEEPiInspiratory thresholdIncrease work of breathingDiaphragm at a suboptimal positionPatient-ventilator asynchronyIneffective triggeringBrainCardiacDiaphragmEndocrineThanks