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pAp inhibition of histone poly(ADP-ribosyl)ation PARP-1 catalysed poly(ADP-ribosyl)ation of histone H1 was measured as described in the Materials and methods section in the presence of the indicated concentrations of pAp. Elie Toledano et al. Biochem. J. 2012;443:485-4902012 by Portland Press Ltd