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1、Basic Principles of Obesity Therapy天马行空官方博客:http:/ ;QQ:1318241189;QQ群:175569632Obesity TherapyAdipose tissueEnergy IntakeEnergy Expenditure天马行空官方博客:http:/ ;QQ:1318241189;QQ群:175569632Relationship Between Rate of Weight Loss and Gallstone FormationIncidence of Gallstone Formation (% subjects/wk)Weins
2、ier et al. Am J Med 1995;98:115. Reprinted with permission from Excerpta Medica.Rate of Weight Loss (kg/wk)00.511.522.5123456789Prevention of Gallstone Formation by Prevention of Gallstone Formation by Ursodeoxycholic Acid During Rapid Weight LossUrsodeoxycholic Acid During Rapid Weight LossNew Gall
3、stones (%)*Shiffman et al. Ann Intern Med 1995;122:899.Sugerman et al. Am J Surg 1995;169:91.Ursodeoxycholic Acid (mg/d)0300600 12000300600 1200VLCD = very-low-calorie diet.16 wk of VLCD*6 mo after gastricbypass procedure28%8%3%2%32%13%2%6%Short-term Obesity Therapy Does Not Result in Long-term Weig
4、ht LossChange in Weight (kg)Wadden et al. Int J Obes 1989;13 (Suppl 2):39.5-yearFollow-up1-yearFollow-upEnd ofTreatmentBaselineDiet aloneBehavior therapyCombined therapyLong-term Weight Loss is Improved with Long-term Maintenance TherapyWeight Loss (%)Perri et al. J Consult Clin Psychol 1988;56:529.0123 456789 10 11 12Time (mo)13 14 15 16 17P P 0.05 40Diet, Exercise, Behavior Tx+Pharmaco-therapyWith co-morbidities+SurgeryWith co-morbidities+BMI Category (kg/mBMI Category (kg/m2) )