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1、施乐辉初次膝关节施乐辉初次膝关节产品介绍产品介绍12012 Proprietary and Confidential: Do not disclose, distribute or otherwise reproduce this information without written consent of an officer of Smith & NephewHeadquarters - London, U.K.CEO - Olivier Bouhon, Revenue - $4,100million ( 2013 ) Employees - 11,000 ( 2013 )Thomas J
2、ames SmithSmith & Nephew Recon Headquaters in Memphis / USA2Enter Name of Presentation (View menu - Header and Footer)7/21/20241856年 Thomas James Smith 于英国Hull开设药局1896年 Smith的侄子Horatio Nelson Smith加入成为 Smith & NephewSmith & Nephew19861986年年, 收购了Richards Medical Company，为医疗行业的引导者IMS data，2009骨科领域主流公司
3、发展状况Import Local mix 50/50 in 2018Surpasses Todays US Market VolumeFuture Knee ProceduresCAGR09-15CAGR15-24Import28.3%12.5%Local49.2%22.6%*CAGRs based on best estimate scenario52024/7/2162024/7/21Trends In TKRTKRs In Younger Patients- 60% Males 65- 40% Females 98% 10-yr survivorship1No one else has
4、an industry-exclusive 30 year wear claim for LEGION CR and PS because no one else has VERILAST Technology2VersatilitySeamless options for diverse surgical challengesProven designs allow natural anatomic reconstruction and offer patient-appropriate materialsEaseEasy, intuitive instrumentationOR Effic
5、iencies of VISIONAIRE Patient-matched Technology + LEGION CR Porous KneesclaimTrademark of Smith & Nephew. Certain marks Reg. US Pat. & TM Off.79对比对比GII发扬发扬继承继承XLPE -高交联垫片更少磨损高交联垫片更少磨损股骨髁新设计股骨髁新设计 -更宽泛适应症更宽泛适应症股股骨工具独特设计骨工具独特设计-使用更加方便节省手术时间使用更加方便节省手术时间外旋截骨外旋截骨 -更多假体类型适用更多术式更多假体类型适用更多术式-优良的髌骨轨迹优良的髌骨轨迹
6、-最大最大155高屈曲高屈曲-解剖型胫骨托设计解剖型胫骨托设计-相同的胫骨垫片设计相同的胫骨垫片设计产品特点产品特点FeatureBenefits1黑晶股骨髁（Oxinium Femoral）+高交联聚乙烯（XLPE）市场上最为耐磨的膝关节假体2完美的髌骨沟设计和Q角设计避免了髌骨弹响与髌骨前区疼痛3可配合Visionaire个性化截骨模块精确匹配患者解剖，减少手术时间4股骨髁假体可安装修补块可适用复杂初次手术需求5解剖型胫骨托更为精密的患者匹配度6MIS 工具设计缩短术后恢复时间7工具简单易用减少术中（手术）时间，满足术中灵活性 （便于术中PS/CR切换）8外旋3截骨与翻修系统可匹配817/
7、21/2024外旋截骨器Guide set 2-6 for LegionGuide set 0 for GIIDrill holes for DCF blockLMLM四合一截骨板12mm9.5mm9.5mmLegionGIILMLM83截骨后LegionGIILMLM84假体植入后9.5mm9.5mm7mmLegionGIILMLM85LEGION 的含义的含义“强大的古罗马军团；众多的强大的古罗马军团；众多的”86LEGION可交换性 87同样的同样的AP截骨截骨88符合人体的解剖 假体几何结构假体几何结构J 曲线，多中心半径设计曲线，多中心半径设计符合大多数股骨部件的尺寸符合大多数股骨部
8、件的尺寸89符合人体的解剖 关节活动中髌骨滑动槽逐渐靠近中线关节活动中髌骨滑动槽逐渐靠近中线0中线中线6090外侧需要松解的几率：相比竞争对手的外侧需要松解的几率：相比竞争对手的8-15%，LEGION只有只有3%90施乐辉是唯一一家公司提供不对称解剖型胫骨假体施乐辉是唯一一家公司提供不对称解剖型胫骨假体的公司的公司对称型胫骨平台对称型胫骨平台过大过大对称型胫骨平台对称型胫骨平台过小过小解剖型胫骨平台解剖型胫骨平台正好正好符合人体的解剖 91高屈曲设计Tightly radiused posterior condylesAllows for deep flexion without the r
9、isk of edge loadingChamfered anterior postDesigned to eliminate patellar component impingement7 of total posterior tibial slopeRelieves ligament tension and promotes femoral rollback最大155高屈曲设计Trademark of Smith & Nephew. Reg. US Pat. & TM Off.LEGION股骨部件 LEGION Revision &CR、PSOXINIUM及及CoCr材料材料尺寸尺寸 2-
10、6号号SPC设计设计AP box截骨相等截骨相等LEGION CRLEGION PSLEGION Rev93LEGION胫骨部件GII & LEGION相同处相同处材料材料=钛合金钛合金尺寸尺寸 1-8号号不对称设计不对称设计相同锁定机制相同锁定机制高抛光表面高抛光表面GII2.3 mm厚度厚度3后倾后倾LEGION5.5 mm厚度厚度0后倾后倾GII（male taper）LEGION （Female taper）94LEGION胫骨衬垫 GII - CPE尺寸：1-8号厚度： Standard 9, 11, 13, 15, 18 mm PS High Flex 9, 11, 13, 15,
11、 18, 21, 25 mm Constrained 11, 13, 15, 18, 21, 25 mmLEGION - XLPE尺寸：1-6号厚度： STD：High Flex 9, 11, 13 and 15mm Constrained：11,13,15,18mm95Based on in-vitro wear simulation testing, the LEGION Primary Knee System with VERILAST technology is expected to provide wear performance sufficient for 30 years o
12、f actual use under typical conditions. The results of in-vitro wear simulation testing have not been proven to quantitatively predict clinical wear performance. Also, a reduction in total polyethylene wear volume or wear rate alone may not result in an improved clinical outcome as wear particle size
13、 and morphology are also critical factors in the evaluation of the potential for wear mediated osteolysis and associated aseptic implant loosening. Particle size and morphology were not evaluated as part of the testing. Trademark of Smith & Nephew. VERILAST Technology with LEGION Primary Knee System
14、Exclusive30yearwearperformance*claimLEGION Total Knee SystemVERILAST Technology the power of simplicity Trademark of Smith & Nephew. Reg. US Pat. & TM Off.Legion/Genesis II系统系统人工全膝关节置换的明智选择人工全膝关节置换的明智选择987/21/2024Confidential For internal use only by Smith & Nephew employees. Do not disclose or distribute to third parties. 99GII/LegionTC-PlusS BDynamic100
