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1、Emulsion-Based Delivery Systems for Lipophilic Bioactive Components用于亲脂生物活性成分的乳液型输送系统ABSTRACT: There is a pressing need for edible delivery systems to encapsulate, protect, and release bioactive lipids within the food, medical, and pharmaceutical industries. 在食品，医疗，制药行业中食用传送系统封装，保护和释放生物活性脂质有迫切需要。The
2、 fact that these delivery systems must be edible puts constraints on the type of ingredients and processing operations that can be used to create them. 事实上，这些输送系统必须限制可食用组分的类型并且可以用来创建它们的加工操作。Emulsion technology is particularly suited for the design and fabrication of delivery systems for encapsulatin
3、g bioactive lipids. 乳液技术特别适合用于封装生物活性脂质的输送系统的设计和制造。This review provides a brief overview of the major bioactive lipids that need to be delivered within the food industry (for example,-3 fatty acids, carotenoids, and phytosterols), highlighting the main challenges to their current incorporation into f
4、oods.此评论提供了需要在食品工业内递送的主要生物活性脂质的简要概述（例如，- 3脂肪酸，类胡萝卜素，和植物甾醇），突出了他们目前掺入食品的主要挑战。We then provide an overview of a number of emulsion-based technologies that could be used as edible delivery systems by the food and other industries, including conventional emulsions, multiple emulsions, multilayer emulsion
5、s, solid lipid particles, and filled hydrogel particles. 然后我们提供一些乳液为基础的技术概述，可以作为食品和其他行业的可食用输送系统，包括常规乳化剂，多重乳化剂，多层乳化剂，固体脂质颗粒，填充水凝胶颗粒。Each of these delivery systems could be produced from food-grade (GRAS) ingredients (for example, lipids, proteins, polysaccharides, surfactants, and minerals) using sim
6、ple processing operations (for example, mixing, homogenizing, and thermal processing). 这些递送系统中的每一个可以从食品级（GRAS）的成分（例如，脂质，蛋白质，多糖，表面活性剂，和矿物质）采用简单的处理操作来生产（例如，混合，均质，和热处理）。For each type of delivery system, we describe its structure, preparation, advantages, limitations, and potential applications. 对于每一种类型
7、的传送系统，我们描述了它的结构，准备，优点，局限性和潜在的应用。精选文档This knowledge Can be used to facilitate these lection of the most appropriate emulsion-based delivery system for specific applications.这方面的知识可以用来促进为特定的应用选择最合适的乳液基传送体系。Keywords: bioactive lipids, delivery systems, emulsions, functional foods, nutraceuticals, struc
8、tural design关键词：生物活性脂质，输送系统，乳化剂，功能性食品，营养制品，结构设计IntroductionA number of industries need to deliver lipophilic functional components in an edible form, including the food, pharmaceutical,and medical industries. 许多行业需要提供可食用形式的亲脂性功能组件，包括食品，医药和医疗行业。These lipophilic components may be a diverse range of su
9、bstances, including bioactive lipids, flavors, antimicrobials, antioxidants, and drugs (Ubbink 2002; Shefer and Shefer2003; Chen and others 2006; Ubbink and Kruger 2006). 这些亲脂性成分可以是各种各样的物质，包括生物活性脂质，香料，抗菌剂，抗氧化剂，和药物。In this article, we will primarily focus on the delivery of bioactive lipids that prov
10、ide specific health benefits to humans, such as -3 fatty acids,carotenoids, and phytosterols. 在这篇文章中，我们将主要集中给人类提供特定的健康利益的生物活性脂质的输送，如- 3脂肪酸，类胡萝卜素和植物甾醇。Nevertheless, the same types of delivery system can also be used to encapsulate other types of lipophilic functional components. 然而，同样类型的传递系统也可用于封装其他类
11、型的亲脂功能组分。In many cases, it is advantageous to deliver bioactive lipids in an aqueous medium because this increases their palatability, desirability, and bioactivity. 在许多情况下，这有利于在含水介质中提供生物活性脂质因为这增加了他们的适口性，期望，和生物活性。For example, a bioactive lipid might be incorporated into a beverage or food that could
12、 be consumed by drinking or eating. 例如，一种生物活性的脂质可以被纳入一种饮料或食物，可以饮用或食用。Nevertheless, there are often technical challenges that need to be overcome before a lipophilic component can be successfully incorporated within an aqueous-based delivery system.然而，亲脂性成分可以成功地结合在基于水的输送系统之前经常有技术挑战需要克服。Bioactive lipi
13、ds differ widely in their molecular properties (for 精选文档example, molecular weights, structures, functional groups, polarities, and charge), which leads to differences in their physicochemical and physiological properties (for example, solubility, physical state, rheology, optical properties, chemica
14、l stability, surface activity, and bioactivity). 生物活性脂类分子性质有很大的不同（例如，分子量，结构，功能基团，极性，和电荷），从而导致其物理化学和生理特性不同（例如，溶解度，物理状态，流变学，光学特性，化学稳定性，表面活性和生物活性）。Consequently, delivery systems often have to be designed to address the specific molecular, physicochemical, and physiological concerns that are unique to e
15、ach bioactive lipid. 因此，传送系统往往需要设计来解决特定的分子，每个生物活性脂质独特的物理化学和生理相关问题。An edible delivery system for bioactive lipids must perform a number of different roles. 具有生物活性的脂质的可食性输送系统必须执行不同的角色。First, it should serve as a means of encapsulating the bioactive lipid into a physical form that can conveniently be i
16、ncorporated into foods or beverages. 首先，它应作为生物活性脂质封装成可以方便地掺入食品或饮料的物理形式的手段。Second, the delivery system should be compatible with the particular food or beverage that it will be incorporated into; that is, it should not adversely affect the appearance, flavor, texture, or shelf life of the product. 其次，传送系统应该与特定的食品或饮料兼容，它可能包含在其中，也就是说，它不应该对食品的外观，风味，质地，或货架期产生不利影响。Third, it may have to protec
