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1、药品标准质量标准标准品国际标准品参比标准对照品规格药品质量控制分析质量控制性状无臭异臭熔点熔距毛细管熔点测定热台熔点测定沸程凝点不溶性微粒颗粒细度膨胀度分子大小微晶结晶细度结晶性一般鉴别试验鉴别旋光计阿贝折射计浸入折射计限度检查有色杂质有关物质吸光度吸光系数吸光度比值澄清度氯化物硫酸盐重金属砷盐碘化物铁盐氰化物drug standardquality standardstandard substanceinternational standard substancereference standardreference substancespecificationdrug quality co
2、ntrolanalytical quality controlcharacteristicsodorlessforeign odormelting pointmelting rangecapillary melting point determi-nationhot stage melting point determi-nationboiling rangecongealing pointparticulate matterfineness of the particlesswelling degreemolecular sizemicrocrystalcrystal fineness cr
3、ystallinitygeneral identification testidentificationpolarimeterAbbe refractometerimmersion refractometerlimit testforeign pigmentrelated substanceabsorbancespecific absorbanceabsorbance ratioclaritychloridesulfateheavy metalarsenic saltiodideiron saltcyanide钡盐钙盐易碳化物易氧化物醚溶性酸性物酸中和容量热原异常毒性衰变放射性核纯度放射性浓度
4、索氏脂肪抽提器丹氏浓缩器不皂化物羟值烷氧基测定范氏氨基氮测定法砷斑炽灼残渣蒸发残渣不挥发物总固体过氧化值干燥失重相溶解度分析装量差异最低装量含量测定含量均匀度溶出度崩解时限药物释放相对密度表观黏度比特性黏度运动黏度旋转黏度计落球黏度计稳定性试验总氮量比重瓶法韦氏比重秤法结冻试验抽针试验barium saltcalcium saltreadily carbonizable substancereadily oxidizable substanceether-soluble acidic matteracid-neutralizing capacitypyrogenundue toxicityde
5、cayradionuclide purityradioactive concentrationSoxhlet extractorDanish concentratornon-saponifiable matterhydroxyl valuealkyloxy determinationvan Slyke methodarsenic stainresidue on ignitionresidue on evaporationnon-volatile mattertotal solidperoxide valueloss on dryingphase solubility analysisconte
6、nt uniformityminimum fillassayuniformity of dosage unitsdissolutiondisintegrationdrug releaserelative densityapparent viscosityspecific intrinsic viscositykinematic viscosityrotating cylinder viscometerfalling sphere viscometerstability studynitrogen contentpycnometric methodhydrostatic method, West
7、phalbalance methodfreezing testconsistence test悬浮时间共沸法甲苯蒸馏法挥发油测定器滴定液标准比色液耐用性计算机辅助药物分析模式收敛特征特征选择试验集训练集校正集预示集岭回归响应面信号处理图象分析库检索变量校正多变量校正反向传播最优化方法窗口图解技术色谱响应函数色谱优化函数混合物设计统计技术叠加分辨率图示法数值分类法系统矩阵组合法双波长一元线性回归法多波长直线回归法系数倍率法最小二乘法自适应最小二乘偏最小二乘法非线性迭代偏最小二乘P矩阵法正交函数法卡尔曼滤波法suspension timeazeotropic methodtoluene disti
8、llation methodvolatile oil determination apparatusvolumetric solution, VSstandard color solutionruggednesscomputational pharmaceutical analysis,computer-aided pharmaceutical analysispatternconvergencefeaturefeature selectiontest settraining setcalibration setprediction setridge regressionresponse su
9、rfacesignal processingimage analysislibrary searchingvariate calibrationmultivariate calibrationback propagationoptimization methodwindow diagram techniquechromatographic response function, CRFchromtographic optimizationfunction, COFmixture design statistic techniqueoverlapping resolution mapsnumeri
10、cal taxonomysystem matrix combination methoddual-wavelength linear regression methodmulti-wavelength linear regression methodK-ratio method, signal multiplier methodleast square methodadaptive least squarepartial least square methodnonlinear iterative partial least squareP-matrix methodorthogonal fu
11、nction methodKalman filtering method适应卡尔曼滤波法卡尔曼增益线性学习机主成分分析主成分回归法逐步判别分析目标因子分析对应因子分析迭代目标转换因子分析法遗忘因子法特征向量投影非线性映射人工神经网络节点线性规划法共轭梯度法专家系统人工智能系统模型测量模型模型化与参数估计决策规则n维空间超平面相似性K最近邻域法快速傅里叶变换交互证实误差修正反馈法负反馈过程分析输出层输入层隐含层碘仿反应丙烯醛反应缩合反应异腈化苯N一溴丁二酰亚胺滴定法永停滴定法两相滴定剩余碱水解法催化热滴定adaptive Kalman filtering methodKalman gainlin
12、ear learning machineprincipal component analysis, PCAprincipal component regression methodstepwise discriminate analysistarget factor analysiscorrespondence factor analysisiterative target transform factor analysis methodforgetting factor methodeigenvector projectionnonlinear mappingartificial neura
13、l networknodelinear programming methodconjugate gradient methodexpert systemartificial intelligencesystem modelmeasurement modelmodeling and parameterestimationdecision rulen-dimensional spacehyperplanesimilarityK-nearest neighbor methodfast Fourier transformcross-validationerror correct feed-back m
14、ethodnegative feedbackprocess analysisoutput layerinput layerhidden layeriodoform reactionacrolein reactioncondensation reactionphenyl isocyanideN-bromosuccinimide titrationdead-stop titrationdiphasic titrationresidual basic hydrolysis methodcatalytic thermometric titration非水催化热滴定提取重量法提取容量法四苯硼钠雷氏铵雷氏盐利伯曼试验马奎斯试验溴化氰试剂本内迪克特试剂茚三酮试剂酸性碘铂酸盐溶液曼德林试剂松柏醇
