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1、 美源康富ABD活性因子与癌症相关研究美源康富ABD活性因子增加杀手T细胞杀伤力，预防癌症美源康富ABD活性因子临床证明能够促进健康人体白细胞合成更多谷胱甘肽，为白细胞的分化和增生提供“食粮”，增加杀手T细胞对癌细胞的杀伤力。科学实验证明，美源康富ABD活性因子能降低癌症的发生率。美源康富ABD活性因子中和自由基，排出致癌物，降低细胞癌变风险在引起细胞癌变的因素中，自由基和致癌物是罪魁祸首。ABD活性因子临床证明能够促进人体所有细胞合成更多谷胱甘肽，谷胱甘肽是细胞的“抗氧化剂之王”和“最强排毒剂”。它由细胞自己产生，是内源性的抗氧化剂，可以中和细胞内的自由基。目前已知的4000多种外源性的抗氧
2、化剂，例如维他命、鱼油和白藜芦醇等，都要通过谷胱甘肽才能有效发挥作用。同时，谷胱甘肽还能与已知的所有致癌物结合，把它们变为无害状态，通过谷胱甘肽转移酶随尿排出体外。因此，美源康富ABD活性因子降低了细胞癌变风险。美源康富ABD活性因子减少化疗放疗副作用，提升造血功能，延长寿命10%-40%ABD活性因子为细胞补充必不可少的生命因子谷胱甘肽，增加癌症患者正常细胞的生命力，使正常细胞能够抵抗放化疗的杀伤力，在治疗中自我保护。另外，谷胱甘肽可以排除化疗残留的药物毒素，保护肝肾。临床研究表明，美源康富ABD活性因子可大大降低放化疗的副作用，提升患者体重，提高白细胞和红细胞计数，提升患者生活质量。双盲对
3、照实验证明，服用后的患者的存活期比未服用患者提高10%-40%。美源康富美源康富ABD活性因子抑制癌细胞活性癌细胞和正常细胞一样，都有自我合成谷胱甘肽的机能。研究表明，癌细胞中的谷胱甘肽含量高于正常，这是因为癌细胞的分裂活性高于正常细胞，需要合成更多谷胱甘肽来维持活性。美源康富ABD细胞因子，作为谷胱甘肽合成的前驱物，会启动癌细胞中谷胱甘肽合成系统的负反馈机制，抑制癌细胞产生谷胱甘肽，从而使癌细胞活性降低，提升放化疗效果。1. Dietary Milk Proteins Inhibit the Development of Dimethylhydrazine-Induced Malignanc
4、yR. Papenburg1, G. Bounous1, D. Fleiszer1, P. Gold2Departments of1Surgery and2Medicine, The Montreal General Hospital and McGill University, Montreal, Quebec, CanadaTUMOR BIOL11: 129-136, 1990Abstract:This study investigated the influence of two formula diets containing 20 g/100 g diet of either whe
5、y protein concentrate or casein, or Purina mouse chow on 1,2dimethylhydrazine (DMH)-induced colon carcinoma in A/J mice. Four weeks after the 24thDMH treatment the incidence of tumor and tumor area in the whey protein-fed mice was substantially less in comparison to either the casein or Purina group
6、s. The Purina group exhibited the greatest tumor burden. At the end of the experiment all animals continuously fed the whey protein diet were found to be alive, whereas 33% of those on the casein or Purina diet had died. Animals fed Purina diet for 20 weeks and then switched to either milk protein d
7、iet for a further 8 weeks exhibited a decrease in tumor burden as compared to those animals fed the Purina diet continuously. Body weights were similar in all dietary groups. In conclusion, a whey protein diet appears to significantly influence the development of chemically induced colon tumors and
8、the short-term survival of mice.研究主题口服美源康富ABD活性因子抑制二甲肼诱导的恶性肿瘤研究目的建立二甲肼（DMH）诱导大肠癌A/J小鼠的模型，研究食用美源康富ABD活性因子、酪蛋白和Purina鼠粮对该模型的影响。研究内容30只小鼠被分为三组，分别食用含20%活性美源康富ABD活性因子配方鼠粮、含20%酪蛋白配方鼠粮和Purina鼠粮，食用三个星期后开始每周注射二甲肼以诱导大肠癌模型，共注射24次，注射期间鼠粮配方不变。注射周期结束后4周，取小鼠大肠观察。研究结果数据显示，活性美源康富ABD活性因子组的肿瘤发生率和肿瘤面积明显低于酪蛋白组和Purina组，P
9、urina组的肿瘤负担最重。实验结束时，ABD活性因子组所有小鼠存活，而其他两组各有33%的小鼠死亡。小鼠食用Purina鼠粮20周后， ABD活性因子配方鼠粮8周，肿瘤负担比持续食用Purina的小鼠降低。三组小鼠体重相似。表1是食用不同饲料的小鼠的肿瘤发展情况。前三组是小鼠分别食用美源康富ABD活性因子、酪蛋白和Purina鼠粮28周时的数据，后两组是小鼠食用Purina20周后改食美源康富ABD活性因子或酪蛋白8周时的数据。各组小鼠在食用前后体重无明细差异。美源康富ABD活性因子组的肿瘤数量和面积明显小于酪蛋白组和Purina组。在Purina组改食用美源康富ABD活性因子后，小鼠的肿瘤
10、数量和面积明细小于改食酪蛋白组。（n=10，p0.05）ABDABD活性因子酪蛋白PurinaPurina/ABDPurina/酪蛋白起始体重21.70.521.50.721.90.821.90.422.00.7结束体重21.50.321.80.419.70.721.31.021.00.6肿瘤数量8.41.524.73.035.92.615.13.221.74.3肿瘤面积38.86.490.910.6160.011.447.910.477.710.9表2 是食用不同鼠粮对小鼠存活率的影响，食用ABD活性因子显著提升大肠癌小鼠的存活率。ABDABD活性因子酪蛋白Purina28周时死亡率0%33
11、%33%研究结论美源康富ABD活性因子明显抑制化学诱导大肠癌的发生和发展，并增加小鼠的短期存活率。文献来源 R. Papenburg, G. Bounous, D. Fleiszer, P. Gold，肿瘤生物学，1990年第11期129-136页2. Whey Proteins in Cancer PreventionG. Bounous1, G. Batist2 and P. Gold31Professor of Surgery, McGill University, and Career Investigator of the Medical Research Council of Ca
12、nada, 2Director, Experimental Therapeutics, Department of Oncology, McGill University, 3Chairman, Department of Medicine, McGill University, and Physician-in-Chief, The Montreal General HospitalCANCER LETTERS, 57: 91-94, 1991Epidemiological and experimental studies suggest that dietary milk products
13、 may exert an inhibitory effect on the development of several types of tumors. Some recent experiments in rodents indicate that the antitumor activity of the dairy products is in the protein fraction and more specifically in the whey protein component of milk. We and others have demonstrated that wh
14、ey protein diets result in increased glutathione (GSH) concentration in a number of tissues, and that some of the beneficial effects of whey protein intake are abrogated by inhibition of GSH synthesis. Whey protein is particularly rich in substrates for GSH synthesis. We suggest that whey protein ma
15、y be exerting its effect on carcinogenesis by enhancing GSH concentration.研究主题美源康富ABD活性因子预防癌症研究综述临床和科学研究显示，某些牛奶制品有可能对几种癌症肿瘤有抑制作用。最近一些针对啮齿类动物的实验表明，这种抗肿瘤的特性来自牛奶乳清中的一些特定的蛋白因子。我们的研究发现，加入乳清蛋白的饲料能够增加很多组织中的谷胱甘肽浓度，当阻断谷胱甘肽合成通路，就消除了食用乳清蛋白带来的益处。乳清蛋白中富含谷胱甘肽合成所需的原料。我们推断，美源康富ABD活性因子有可能通过提升谷胱甘肽浓度，起到预防癌症的效果。文献来源 G. Bounous, G. Batist, P. Gold， 癌症文献，1991年57期91-94页3. The Use of a Whey Protein Concentrate in the Treatment of Patients with Metastatic Carcinoma: APhaseI-IIClinicalStudyRenee S. Kennedy1, George P. Konok1, Gustavo Bounous2, Sylvain Baruchel3and Timo
