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1、老年髋部骨折围手术期 相关问题,Pre-operative,Treatment strategy Surgical fixation of fractured hips remains the standard of care,Pre-operative,Evaluation Complete history, physical examination, laboratory examinations Assessment of the surgical risks System deficits identified, and corrected The American Associati
2、on of Anaesthetists grading,Pre-operative,Pain：acetaminophen Approximately 40% of patients moderate renal dysfunction (eGFR 60 ml/min/1.73m2) Opioids：with caution NSAIDS: relatively contrindicated,Pre-operative,Preoperative traction Abandoned,Pre-operative,Preoperative DVT prophylaxis Pressure gradi
3、ent stockings; LMWH: 12h prior to surgery; Aspirin withheld,Pre-operative,Hemoglobin (Hb) Pre-operative anaemia in approximately 40% Pre-operative transfusion considered if: Hb is 9g/dl. Hb is 9 9.9g/dl and there is a history of ischaemic heart disease.,Pre-operative,White cell count Leucocytosis an
4、d neutrophilia common (45%, 60% respectively) at presentation; Marked leukocytosis 17*109 /L may indicate infection (usually chest or urine).,Pre-operative,Platelet count Below 50*109/L normally require pre-operative platelet transfusion.,Pre-operative,Atrial Fibrillation (AF) Ventricular rate of le
5、ss than 100 required. Factors: hypokalemia,hypomagnesemia, hypovolemia, sepsis, pain and hypoxemia. Beta-blockers to control HR,Pre-operative,Diabetes Hyperglycemia is not a reason to delay surgery unless the patient is ketotic and/or dehydrated.,Pre-operative,Dialysis Surgery tailored around the di
6、alysis; Urgent surgery may necessitate heparin-free dialysis,Pre-operative,Time to surgery Early surgery (2436 h) recommended No delay for patients mild to moderate hypertension (systolic 180 mmHg and diastolic 110 mmHg) No awaiting echocardiography No delay for minor electrolyte abnormalities,Pre-o
7、perative,Reasons to optimise Severe anemia Hb 150mmol/l and potassium 6.0 mmol/l. Uncontrolled diabetes,Pre-operative,Reasons to optimise Uncontrolled or acute onset left ventricular failure Correctable cardiac arrhythmia, with a ventricular rate 120 bpm Chest infection with sepsis Reversible coagul
8、opathy,Intra-operative,Antibiotics Antibiotics administered before skin incision Hospital antibiotic protocols followed,Intra-operative,Anaesthetic considerations Regional anesthesia recommended Keep intra-op diastolic 60mmHg,Intra-operative,Intravenous fluids Many patients hypovolemic at the time o
9、f surgery Colloids reduce hospital stay and improve outcome,Post-operative,Pain management Post-op epidural anesthesia less common Regular acetaminophen throughout perioperative period. NSAIDS used with extreme caution, and contraindicated in those with renal dysfunction,Post-operative,Pain manageme
10、nt Opioids (and tramadol) used with caution in patients with renal dysfunction Oral opioids avoided, and intravenous doses halved with a halved frequency Codeine should not be administered (constipating, emetic, perioperative cognitive dysfunction),Post-operative,DVT prophylaxis LMWH; Warfarin; Riva
11、roxaban 10-35 days,Post-operative,Oxygen Supplemental oxygen post-operatively for at least 24 hours Some evidence supports oxygen therapy for the first 72 h,Post-operative,Fluid balance Hypovolemia common Early oral fluid intake encouraged Urinary catheters removed as soon as possible Routine transf
12、usion in asymptomatic patients with a haemoglobin level 80 g/L not be required.,Post-operative,Postoperative delirium Common (25%-50%) with hip surgery Factors: hypoxia, hypoglycaemia, major fluid and electrolyte imbalances, sepsis and major organ impairment Prophylactic low-dose haloperidol may red
13、uce severity and duration of delirium,Post-operative,Nutrition Up to 60% of hip fracture patients clinically malnourished on admission The calorie and protein density of hospital food often poor,Post-operative,1、热量：热氮比=100150:1 2、蛋白（按0.15-0.2g氮/kg/d）计算（1g氮=6.25g氨基酸） 3、糖脂肪混合能源中：糖/脂 =3/2 4、产热效能：1g糖=1g
14、蛋白质=4.1 kcal，1g脂肪=9.3 kcal,实例,男，88岁，股骨颈骨折半髋术后第4天 体检：HR: 90bpm，BP：120/70mmHg，T：36.5，W：55kg，SaO2 98% 精神稍微萎靡，神智清，认知能力好，贫血貌，伤口干燥，无红肿。双肺呼吸音清（CT提示：胸腔积液），阴囊水肿，入量400ml，尿量1900ml，可少量进食，保留尿管，大便通畅有腹泻7-8次/天,实例,血常规：WBC 4.05109/L；RBC2.96 1012/L，HGB 69g/L; Hct 0.198; Lymph: 0.640109/L 血生化： 白蛋白：26.1 g/L，球蛋白：14.6 g/L
15、 ，K：3.15 mmol/L, Ca 1.91 mmol/L , Iphos 0.56 mmol/L,实例,1、每日氮需要量：0.17555=9.6g，即9.66.25=60g氨基酸 2、每日需要热量：9.6125=1200 kcal 糖供热：12003/5=720 kcal/d 脂肪供热：12002/5=480 kcal/d 4、补充脂肪：4809.352 g 5、补充葡萄糖：7204.1175 g,实例,预计补液量：1750.1=1750ml（3L袋内糖浓度10%）.2000ml 20%脂肪乳（力能）250ml（50g：488 kcal）补入250 ml 氨基酸（法谱）（8.5%/250ml）：6021.53(约750 ml).750 ml 0.9NaCL：500ml（4.5g钠）500 ml 糖用50% GS补入：175 50%=350 ml350 ml,实例,预计补液量：1750.1=1750ml（3L袋内糖浓度10%）.2000ml 20%脂肪乳（力能）250ml（50g：488 kcal）补入250 ml 氨基酸（法谱）（8.5%/250ml）：6021.53(约750 ml).750 ml 0.9NaCL：500ml（4.5g钠）500 ml 糖用50% GS补入：175 50%=350 ml350 ml,实例,10KCL 45ml （可另加口服“补达秀 1.0
