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1、LigaSureTM 的临床应用,Energy Based Tissue and Vessel Fusion,Vessel ligation is a critical component of all surgical dissection. 血管的结扎是所有外科手术分离中的关键部分,Vessel and Tissue Ligation What are your choices?,Ligation Techniques,Manufacturers Recommended Range of Vessel Size for Application (mm),0.5,1.0,1.5,2.0,2.
2、5,3.0,3.5,4.0,4.5,5.0,5.5,6.0,6.5,7.0,7.5,8.0,8.5,9.0,9.5,10.0,Suture,Clips,Staples,Monopolar ES,Bipolar ES,Ultrasonic Coag,Vessel Sealing,*,*,3 sizes of clips and appliers,Vascular Staples,Vessel and Tissue Fusion 脉管和组织融合技术,Electrosurgical Technology That Combines,Pressure and Energy 压力和能量,To Creat
3、e a Fusion Zone 产生一个融合带,Tissue and Vessel Fusion,an advance in a unique electrosurgical technology that combines pressure and energy to create a fusion zone 一种先进电外科技术将压力和能量结合从而产生融合带,Developed in response to surgeon requests for an additional option to current vessel ligation methods 根据外科医生的需求发展的技术，从
4、而提供目前血管结扎手段以外的方法。,Vessel Fusion System 脉管闭合系统,Generator 主机 Bipolar instrument configuration 双极工作模式 Low Voltage - 180V 低电压180V High Current - 4A 高电压4A Tissue Response 组织反馈技术 Instruments 器械 High pressure 高钳口压力 Open (reposable and single use) 开放器械（可重新组装的和一次性使用的） Laparoscopic (single use) 腔镜器械（一次性使用）,Sy
5、stem Operation,Applies optimal pressure to vessel/tissue bundle 在血管/组织束上施加最佳的压力 Energy delivery cycle: 能量输送周期： Measures initial resistance of tissue and chooses appropriate energy settings 测量组织的最初电阻并选择适当的能量设定 Delivers pulsed energy with continuous feedback control 输送能量脉冲同时进行持续的反馈控制 Pulses adapt as t
6、he cycle progresses 随循环周期的进行调整能量脉冲 Senses that tissue response is complete and stops the cycle 监测组织反馈当闭合完成时停止能量输送,Fusion Characteristics 融合带的特性,Intimal layers of vessel walls fused 融合血管壁的内膜 Does not rely on a proximal thrombus 不依赖于近端血栓 Permanent 永久性闭合,Tissue Effects of Coagulation Versus Vessel Fusi
7、on 凝血和脉管闭合技术的组织效果的比较,Coagulation relies on vessel shrinkage and a proximal thrombus for vessel occlusion. 凝血依赖于血管的收缩和近端血栓堵塞血管,Vessel fusion fuses the intimal walls of the vessel, completely obliterating the lumen. 脉管闭合技术融合了血管壁的内膜，从而完全封闭管腔。,*Porcine Model,Fusion Characteristics,Plastic-like consisten
8、cy due to collagen remodeling 由于胶原蛋白的重塑，闭合带均一而且富有弹性。 Distinctive, possibly translucent fusion zone 独特的透明闭合带 Withstands greater than three times normal systolic pressure 可承受3倍以上的正常收缩压,Tissue Selection Criteria 选择组织的标准,Veins and arteries up to and including 7mm 达到并包括7mm的静脉和动脉 Tissue bundles containing
9、 vessel(s) or lymphatics 包含有血管或淋巴管的组织束 Lymphatics up to and including 7 mm 达到并包括7mm的淋巴管,Results,High burst strength seals exhibited the following properties: 高破裂压的闭合带具有以下特性： Thin, translucent, plastic-like seal site 薄的透明弹性闭合带 seal zone significantly compressed 被压缩的扁平闭合带 intimal layers of vessel wall
10、s fused 融合血管壁内膜 lateral thermal damage 2mm 外侧热损伤2mm,H & E stained longitudinal section of sealed porcine renal artery H & E染色的猪肾动脉闭合带的纵切面,The seal zone. Note the fused lumen of the vessel walls. 闭合带；注意血管壁已被融合在一起，内腔消失。,Burst Strength Study Results Percent success of fusion zone withstanding 3 times n
11、ormal systolic pressure (360mmHg),Comparison Study Results,Probability of seal failure below 400 mmHg: 在400mmHg压力下闭合带破裂的概率： Ultrasonic coagulator 超声凝血 95.0% Standard bipolar 标准双极 28.0% Clips* 金属夹 0.4% Vessel sealer* 脉管闭合技术 0.2% Ligatures* 缝线 0.0% Probability of failure for ultrasonics and standard b
12、ipolar is significantly higher than other methods 超声刀和标准双极的闭合失败概率明显高于其他方法。 Other methods (*) not statistically different from each other 其他的方法（*）之间没有明显区别。,Healing process,A comparison* of the healing process following ligation with sutures and vessel sealing system have been studied at 7, 14 and 28
13、days. 缝线结扎和血管闭合技术的愈合过程中第7、14和28天比较 At 7 days, both LigaSure and suture sites exhibited gross signs of inflammation. 第7天：“LigaSure 和缝线的部位都有炎症的表现” At 14 days, numerous adhesions were noted at the suture sites whereas the LigaSure seals did not affect any of the surrounding tissue 第14天：“在缝线部位有许多的粘连，而Li
14、gaSure闭合带与周围组织没有粘连” At 28 days : “ numerous evolved adhesions were present at the suture sites. The LigaSure sites were difficult to locate” 第28天：“缝线部位有许多粘连形成，而LigaSure 闭合部位已经难以确认” The potential for seals composed of the patients native tissue reduce the inflammatory response and improves healing pr
15、ocess . 闭合带由患者自身的组织构成，从而减少了炎症反应，促进了愈合过程。,* Comparison of Healing Process Following Ligation with Sutures and Bipolar Vessel Sealing PETERSON, STRANAHAN, SCHMALTZ, MIHAICHUK, COSGRIFF Surgical Technology International,Sutures at 28 days,LigaSure at 28 days,Vessel Fusion Technology,Ensures: Fusion str
16、engths higher than other energy based techniques 闭合强度高于其他的能量技术 Fusion strengths comparable to existing mechanical based techniques 闭合强度与现存的机械闭合技术相当,Vessel Fusion Technology,Ensures: Reliable, consistent, permanent vessel wall fusion 可靠的、一致的、永久性血管壁融合 Minimal thermal spread 最小的热传导 Reduced sticking and charring 较少的粘连和焦痂,Surgical specialties with experience in vessel fusion techno
