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1、Evalution of LV global and regional function in patients with heart failure due to anterior wall myocardial infarction using radionuclide ventriculagraphy Wu Di, Huang Xizheng, Ma Shuping. Heart Diagnose and Treatment Center. Hebei Province Peoples Hospital. Shijiazhuang, Hebei, P.R.China, 050051.Ab
2、stract Objective: To assess left ventricular (LV) global and regional function of systolic and diastolic in the patients with anterior wall myocardial infarction in heart failure, we analyzed high-temporal-resolution LV global and regional time-activity curves obtained from gated radionuclide ventri
3、culargraphy. Materials and Methods: The patients were divided three groups, a control group(G0) of 15 normal peoples, and two groups of patients with previous anterior wall myocardial infarction but without aneurysm, a first group(G1) of 25 patients in NYHA class 0, a second group(G2) of 24 patients
4、 in NYHA class or . The parameters included (1) LV global systolic and diastolic function parameters, (2) LV regional systolic and diastolic function parameters. Results: (1) LV global systolic function: the parameters of LVEF PER 1/3EF 1/3ER in G2 were reduced significantly than that in G0 and G1 (
5、p0.01). (2) LV global diastolic function: the parameters of PFR 1/3FF 1/3FR in G2 were reduced significantly than that in G0 and G1 (p0.01). (3) LV regional systolic function: the parameter of LVREF in G2 were reduced significantly in all LV regional 6 segments than that in G0 and G1 (p0.01). (4) LV
6、 regional distolic function: the parameter of LVR1/3FF in G2 were reduced significantly in all LV regional 6 segments than that in G0 and G1 (p0.01). Conclusion: The development of left ventricular disfunction and heart failure after anterior wall myocardial infarction had produced damage on left ve
7、ntricular global and regional function of systolic and diastolic.Key words Radionuclide ventriculography; Left ventricular myocardial infarction; Heart failure; Left ventricular global and regional function放射性核素心室造影评价前壁心肌梗死后心力衰竭患者左室整体和局部功能吴迪黄希正马淑平 河北省人民医院心脏诊治中心一科河北 石家庄050051摘要目的 我们应用放射性核素心室造影技术对不同 N
8、YHA 分级的前壁心肌梗死患者进行左室总体和局部收缩和舒张功能参数的对比分析。方法 对照组 15 例（G 0） ，前壁心肌梗死 NYHA 0 级 25 例（G 1） ，前壁心肌梗死 NYHA 级 12 例（G 2） 。利用平衡法门控心血池显像技术评价三组的左室总体和局部的收缩与舒张功能。结果 左室整体收缩功能,在 LVEF、PER、1/3EF 、1/3ER 4 个参数中, G2 分别比 G1 和 G0 显著性差异（P0.01 ） 。 左室总体舒张功能，在 PFR、1/3FF 、1/3FR 中，G 2 分别比 G1 和 G0 有显著差异（P0.01） 。 左室局部收缩功能，在以 LVREF 为参
9、数时，G 2 在所有 6 个节段比 G1和 G0 分别有显著下降（P0.01） 。 左室局部舒张功能，在以 LVR1/3FF 为参数时，G 2 在所有 6 个节段比 G0 和 G1 分别有显著下降（P0.01） 。结论 前壁心肌梗死后出现心功能不全或心力衰竭已对左室整体和局部的收缩及舒张功能产生损害。关键词放射性核素心室造影；左室心肌梗死；心力衰竭； 左室收缩和舒张功能。The development of left ventricular disfunction and heart failure is a serious complication after myocardial infa
10、rction. Clinical researchers pay attention to the left ventricular dysfunction due to left ventricular myocardial infarction . Using radionuclide ventriculargraphy at rest, we studied several parameters of systolic and diastolic function of left ventricular included global and regional in a group of
11、 the patients with heart failure and a previous history of anterior wall myocardial infarction. The aim of this study was to characterize the radionuclide parameters that are associated with the occurrence of heart failure after myocardial infarction.Materials and MethodsPatient populationOf patient
12、s who underwent radionuclide ventriculargraphy at rest for evalution of an already diagnosed myocardial infarction. They were selected according to the following exclusion criteria: history of hypertension, diabetes, associated valvular disease, chronic obstructive pulmonary disease, presence of bun
13、dle branch block. Radionuclide ventrculargraphy was performed at least 24 hour after cessation of dosing with nitrate preparations, calcium-channel blocking drugs, and beta-blocking agents. The patients were divided into three groups. The control group (G0) included 15 patients cosidered to have no
14、cardiac disease on the basis of normal electrocardiograms, and no noninvasive or invasive cardiologic evidence for heart disease. The remaining patients were selected because they had suffered an anterior wall myocardial infarction more than 1 month before examination. We define their disease according to World Health Organization(WHO) standardization. These patients were divided into two subgroups according to their New Yor
