《泌尿生殖系统发育课件》由会员分享，可在线阅读，更多相关《泌尿生殖系统发育课件（45页珍藏版）》请在金锄头文库上搜索。
1、Development of Urogenital System,intermediate mesodermnephrogenic cordsurinary system genital system,I. The Urinary Systemnephrotome,nephrogenic cord urogenital sinus pronephrosmesonephros urinary bladder and urethra metanephros (epithelium)(permanent kidney),1. The Kidneys and its Excretory Ducts (
2、1)The pronephros: 4th week cervical regiontransitorynonfunctionalpronephric tubule - degenerate pronephric duct - utilized by mesonephros,(2) The mesonephros later in the 4th week caudal to the pronephrostransitoryfunction ?mesonephric tubules mesonephric ridges mesonephric duct pronephric ductduct
3、and a few tubules persist as genital ducts in male,(3) The Metanephros 5th weekcaudal to the mesonephrospermanentfunctionalureteric bud two sources metanephric mesoderm,mesonephric duct metanephric mesoderm ureteric bud metanephric tubules ureter, renal tubules renal pelvis, major & minor calyces,co
4、llecting tubules one end another endcommunicate invaginated by capillariescollecting tubule nephron,2. The Urinary Bladder and Urethra cloaca urogenital sinus (cranial) bladder M cranial 2 parts of urethra (middle) F urethra spongy urethra (caudal ) vaginal vestibule,3. The Malformations Horse-shoe
5、kidney (2) Ectopic kidney (3) Polycystic kidney (4) Double ureters,Horse-shoe Kidney,Ectopic Kidney,Horse-shoe kidney,Polycystic kidney,Polycystic kidney,Double Ureters,Double Ureters, The development of Genital System 1.Development of the Testis and Ovary The Indifferent Gonads: intermediate coelom
6、ic primordial germ cellsmesoderm epithelium (from the yolk sac) mesonephric ridge primary sex cords gonadal ridge migrateindifferent gonad,(2) Development of the Testis(Y chromosome )mesenchyme sex cords primordial germ cellsinterstitial cells Sertoli cells spermatogonia connective tissue seminifero
7、us tubules testis,(3)Development of the Ovary ( lack Y chromosome)mesenchyme epithelium primordial germ cellsconnective tissue cortical cords oogonium follicular cell primary oocytes primordial follicle ovary,(4) Descent of the Gonads posterior wall of abdomen pelvis ovaryinguinal canal scrotum test
8、is,2. Development of the Genital Ducts The Indifferent Stage mesonephric ducts and tubules paramesonephric ducts(Y-shaped canal) rostral portion para- to mesonephric ducts, open into the body cavity caudal portion fuse together in the midline, caudal end projects into the dorsal wall of the urogenit
9、al sinus and produces the sinus tubercle,(2) Development of The Male Genital Ductsparamesonephric ducts degeneratemesonephric tubules efferent ductusmesonephric duct ductus epididymis, ductus deferens,ejaculatory duct,(3) Development of The Female Genital Ducts mesonephric ducts degenerateparamesone
10、phric ducts female genital ductscranial unfused portions uterine tubesfused portion uterus fornix portion of vagina sinus tubercle vaginal plate remaining part of vagina,3. The Malformation Cryptorchidism (2) Double Uteruses and Bicornuate Uterus (3) Vaginal Atresia (4) Hermaphroditism or Intersexulity,
