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1、龚流柱 中国科学技术大学合肥微尺度物质科学国家实验室，化学系,Gold Catalysis,金属有机化学-均相催化，2010-11-23,General Introduction of Gold,Atomic Number: 79 Atomic Weight: 196.966569 Common Oxidation State: +3, +1,Electron Shell Configuration:,1s2, 2s2 2p6, 3s2 3p6 3d10, 4s2 4p6 4d10 4f14, 5s2 5p6 5d10,5f0 6s1 6p0,Au(I) and Au(III) are abl
2、e to form complexes with heteroatom and unsaturated Hydrocarbons,-Complexes of Gold in Any of Its Oxidation States,Chalk, A. J. Am. Chem. Soc. 1964, 86, 4733 Strahle, J. and Calderazzo, F. et al, Organometallics 1987, 6, 1207 Mingos, D. M. P. et al, Angew. Chem. Int. Ed. Engl. 1995, 34, 1894.,Nesmey
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6、r the Synthesis of Piperidin-4-ones,Cui, L.; Peng, Y.; Zhang, L. J. Am. Chem. Soc. 2009, 131, 8394-8395,Generation of Gold Carbenes for the Synthesis of Dihydrofuran-3-ones,Zhang, L. et al, J. Am. Chem. Soc. 2010, 132, 3258-3259,Synthesis of A-D Ring of Azaspiracid,Synthetic Approach,Mukaiyama Oxida
7、tive cyclization: Inoki, S.; Mukaiyama, T. Chem. Lett. 1990, 67-70,modp = 1-morpholinocarbamoyl-4,4-dimethyl -1,3-pentanedionato,Li, Y.; Zhou, F.; Forsyth, C. J. Angew. Chem. Int. Ed. 2007, 46, 279,Hydroxylation/ Prins Cyclization,Barluenga, J. et al, Angew. Chem. Int. Ed. 2006, 45, 2091,Hydrocarbox
8、ylation of Alkynes,Genet, J.-P. et al, J. Am. Chem. Soc. 2006, 128, 3112,Carboalkoxylation of Alkynes,Possible Mechanism,Cross-Reaction,Reaction of Enantioenriched Substrates,Reaction Mechanism,Dube, P.; Toste, D. F. J. Am. Chem. Soc. 2006, 128, 12062,Intramolecular Hydroamination of Alkynes,Fukuda,
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11、o Alkynes,Zhang, Y.; Donahue, J. P.; Li, C.-J. Org. Lett. 2007, 9, 627,Kusuma, H.; Miyashita, Y.; Takaya, Iwasawa, N. Org. Lett. 2006, 8, 289,Afonsi, M. et al, J. Org. Chem. 2005, 70, 2265,Gorin, D. J.; Davis, N. R.; Toste, F. D. J. Am. Chem. Soc. 2005, 127, 11260,Addition of Azide,Addition of Enol
12、Ethers and Enamines,Sherry, B. D.; Maus, L.; Laforteza, B. N.; Toste, F. D. J. Am. Chem. Soc. 2006, 128, 8132,Aryl Addition to Alkynes,Ferrer, C.; Echavarren, A. M. Angew. Chem. Int. Ed. 2006, 45, 1105,Shi, Z.; He, C. J. Org. Chem. 2004, 69, 3669.,Amination of Allenes,Reaction Mechanism,Nishina, N.;
13、 Yamamoto, Y. Angew. Chem. Int. Ed. 2006, 45, 3314,Liu, Z.; wasmuth, A. S.; Nelson, S. G. J. Am. Chem. Soc. 2006, 128, 10352,Hashmi, A. S. K. et al, Angew. Chem. Int. Ed. 2000, 39, 2285,He, C. et al, J. Am. Chem. Soc. 2006, 128, 1798,He, C. et al, J. Am. Chem. Soc. 2005, 127, 673,Enynes as Substrate
14、s,Hashimi, A. S. K. et al, J. Am. Chem. Soc. 2000, 122, 11553 Echavarren, A. M. et al, Angew. Chem. Int. Ed. 2001, 40, 4754; J. Am. Chem. Soc. 2001, 123, 10511,Echavarren, A. M. et al, Angew. Chem. Int. Ed. 2004, 43, 2402,Luzung, M. R.; Markham, J. P.; Toste, F. D. J. Am. Chem. Soc. 2004, 126, 10858
15、,Cascade Reaction,Reaction Mechanism,Zhang, L.; Kozmin, S. A. J. Am. Chem. Soc. 2005, 127, 6962,Toste, F. D. et al, J. Am. Chem. Soc. 2010, 132, 8276-8277,Polycyclization Reaction Catalyzed by Gold(I),He, C. et al, J. Am. Chem. Soc. 2006, 128, 1798,Functionalization of Alkenes,He, C. et al, J. Am. C
16、hem. Soc. 2005, 127, 673,Oxidative Carbafunctionalization of Alkenes,Zhang, L. et al, J. Am. Chem. Soc. 2010, 132, 1474-1475,Reaction Mechanism,Zhang, L. et al, J. Am. Chem. Soc. 2010, 132, 1474-1475,Olefin Metathesis Mechanism, Catalyst Design and Application,Metathesis:,Metathesis:,History of Olef
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