生物化学代谢总论

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1、 授课老师:授课老师: 陈陈 尚尚 武武 E-mail: E-mail: E-mail: E-mail: 邓邓 庆庆 丽丽 E-mail: E-mail: E-mail: E-mail: BiochemistryBiochemistryBiochemistryBiochemistry is the chemistry of is the chemistry of is the chemistry of is the chemistry of life.life.life.life.BiochemistryBiochemistryBiochemistryBiochemistry is the

2、 science concerned withis the science concerned withis the science concerned withis the science concerned with various chemical molecules various chemical molecules various chemical molecules various chemical molecules in living cells and in living cells and in living cells and in living cells and o

3、rganism and with organism and with organism and with organism and with the reactions and process the reactions and process the reactions and process the reactions and process that they undergothat they undergothat they undergothat they undergo. . . . MetabolismMetabolismMetabolismMetabolismMetabolis

4、m would answer the fundamental Metabolism would answer the fundamental Metabolism would answer the fundamental Metabolism would answer the fundamental questions for Biochemistry.questions for Biochemistry.questions for Biochemistry.questions for Biochemistry.1. 1. 1. 1. How does a cell extract energ

5、y and reducing How does a cell extract energy and reducing How does a cell extract energy and reducing How does a cell extract energy and reducing power from its enviromentspower from its enviromentspower from its enviromentspower from its enviroments? 2. 2. 2. 2. How does a cell synthesize the buil

6、ding How does a cell synthesize the building How does a cell synthesize the building How does a cell synthesize the building blocks of its macromolecules and then the blocks of its macromolecules and then the blocks of its macromolecules and then the blocks of its macromolecules and then the macromo

7、lecules themselves? macromolecules themselves? macromolecules themselves? macromolecules themselves? Living cells must extract Living cells must extract Living cells must extract Living cells must extract energy and reducing power energy and reducing power energy and reducing power energy and reduci

8、ng power from its enviroments.from its enviroments.from its enviroments.from its enviroments.Cells synthesize the building blocks of its Cells synthesize the building blocks of its Cells synthesize the building blocks of its Cells synthesize the building blocks of its macromolecules.macromolecules.m

9、acromolecules.macromolecules.The length of the The length of the The length of the The length of the E. coliE. coliE. coliE. coli chromosome (1.7mm) is chromosome (1.7mm) is chromosome (1.7mm) is chromosome (1.7mm) is depicted in linear form relative to the length of a depicted in linear form relati

10、ve to the length of a depicted in linear form relative to the length of a depicted in linear form relative to the length of a typical typical typical typical E. coliE. coliE. coliE. coli cell (2 cell (2 cell (2 cell (2 m).m).m).m).The total contour length of all The total contour length of all The t

11、otal contour length of all The total contour length of all the DNA in a single human cell the DNA in a single human cell the DNA in a single human cell the DNA in a single human cell is about 2m. An adult human is about 2m. An adult human is about 2m. An adult human is about 2m. An adult human body

12、contains approximately body contains approximately body contains approximately body contains approximately 1010101014141414 cells and thus a total DNA cells and thus a total DNA cells and thus a total DNA cells and thus a total DNA length of 2length of 2length of 2length of 21010101011111111 km.km.

13、km. km.The circumference of the earth The circumference of the earth The circumference of the earth The circumference of the earth is 4is 4is 4is 4101010104 4 4 4 km. The distance km. The distance km. The distance km. The distance between the earth and the sun is between the earth and the sun is bet

14、ween the earth and the sun is between the earth and the sun is 1.51.51.51.5101010108 8 8 8 km. km. km. km.Chapter 1 Introduction of MetabolismChapter 1 Introduction of MetabolismChapter 1 Introduction of MetabolismChapter 1 Introduction of Metabolism 代谢导论代谢导论1.1 1.1 1.1 1.1 代谢的基本概念代谢的基本概念 1.2 1.2 1.

15、2 1.2 代谢的主要特点代谢的主要特点 1.3 1.3 1.3 1.3 代谢的一些基本原理和规律代谢的一些基本原理和规律 1.4 1.4 1.4 1.4 代谢与生物进化代谢与生物进化 1.5 1.5 1.5 1.5 代谢的研究代谢的研究 1.6 1.6 1.6 1.6 重要代谢途径的研究成果回顾重要代谢途径的研究成果回顾 1.7 1.7 1.7 1.7 学习的要求和技巧学习的要求和技巧广义上,代谢指的是生物体与环境之广义上,代谢指的是生物体与环境之 间的物质和能量交换。间的物质和能量交换。狭义上,代谢指的是由细胞内所有化狭义上,代谢指的是由细胞内所有化 学变化组成的高度整合的网络的总称学变化组成的高度整合的网络的总称 ( a highly integrated network of all a highly integrated network of all a highly integrated network of all a highly integrated network of all chemical reactions in a cellchemical reactions in a cellchemical react

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