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1、子宫肌瘤 （myoma of uterus）,徐柏,myoma of uterus,Uterine leiomyomas are the most common pelvic tumors in women of reproductive age, occurring in up to 50%of patients in autopsy series. Composed of smooth-muscle cells within a fibrous tissue matrix.,Causes,细胞遗传学异常 雌激素受体和雌二醇升高,types,Intramural myoma Subserou
2、s myoma Submucous myoma,Pathology,巨检：实性球形结节有假包膜切面呈旋涡状 镜检皱纹状排列的平滑肌纤维，呈旋涡妆,degeneration,玻璃样变 hyaline degeneration 囊性变 cystic degeneration 红色变 red degeneration 肉瘤变 sarcomatous change 钙化 degeneration with calcification,Clinical Presentation,Symptomabnormal uterine bleedingpelvic mass leukorrhagiapelvic pain Pressure and obstructive symptoms Infertility Hemorrhagic anemia,Clinical Presentation,体征与肌瘤的大小、位置、数目有关。质硬、形不规则的包块。,Diagnosis,根据症状、体征及相应的辅助检查。 鉴别：1.妊娠子宫2.卵巢肿瘤3.子宫腺肌病及腺肌瘤4.盆腔炎性包块5.子宫畸形,Treatment 1,随诊观察：肌瘤小、无症状、近绝经期 药物治疗：2.5月妊娠子宫；症状明显1. hysteromyomectomy2. Hysterectomy/ Subtotal ,
