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1、EuroIntervention 2012 Randomised trials22711 FFR and PCI228EuroIntervention 2012 Randomised trials11 FFR and PCIPijls JACC 2007;49:2105- 11Conclusion: five-year outcome of deferral of PCI of intermediate stenosis (FFR 0.75) is excellent.Events at 5 yearsObjective:to investigate the appropriateness o
2、f stenting of a functionally non-significant stenosisStudy:multicenter randomised trialPopulation:patients scheduled for PCI with intermediate stenosis, with FFR measurements immediate before PCI. If FFR 0.75 patients randomised to DEFER group or Performance group. FFR 50% n=496FFR guided: only sten
3、ting if FFR3xULN), any revascularisation at 2 year f-upFAME 2 yearIdentification of all lesions 50% DS planned for PCIMVD patients referred for PCI n=1005FFR guided PCI if FFR 0.8 n=509Angiography guided n=509231EuroIntervention 2012 Randomised trialsFFR and PCI 11 Briguori et al. J Am Coll Cardiol
4、2009;54:2157- 2163Conclusion: a single high loading dose of atorvastatine within 24 hours of PCI reduces the incidence of periprocedural MI in elective statin nave PCI patientsObjective:to assess whether a single dose of atorvastatin 80 mg reduces the rate of peri-procedural myocardial infarctionStu
5、dy:two center, randomised trialPopulation:Statin nave patients scheduled for elective PCI of de novo lesions in native coronary arteriesEndpoints: periprocedural MI (CKMB 3xULN with or without symptoms and/or ECG changes)NAPLES-II trial Randomised n=1348Atorvastatin 80 mg n=676Coronary angiographyNo PCI of native vessel n=338Included N=338Control n=672Coronary angiographyNo PCI of native Vessel n=342Included N=330