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1、面向未来家用医疗检测设备的微纳光学片上传感模型设计面向未来家用医疗检测设备的微纳光学片上传感模型设计摘摘 要要生活水平的提高和人们健康意识的增强，极大推动了医疗健康产业的发展。近年来，家用医疗行业作为朝阳产业，迎合市场需求，具有广阔的前景。家用医疗检测设备可以帮助人们在日常生活中监视身体状况、调整作息，在疾病早期及时就医治疗，有望成为人们健康的第一道防火墙,更好地服务人们健康。传统的医疗检测手段往往都有操作繁琐、设备成本高、分析过程慢等各种缺点，不适合在家用医疗领域推广。相比之下，光子晶体生物传感器具有低成本、易集成、免标签、高精度等诸多优点，更适合于未来家用医疗检测设备的使用。本文介绍了光子
2、晶体的理论知识和传感原理，调研了国内外光子晶体生物传感器的研究现状，运用 Lumerical 等仿真工具研究分析了完美光子晶体、W1 波 L3 微腔和中央大腔的光学性能，总结了结构参数对传感性能的影响，证明了谐振波长和折射率之间的线性关系；并且在此基础上提出了一种多路复用二维光子晶体生物传感器设计方案。在折射率 n=3.48 的硅板上布置三角晶格的圆形空气孔，去除中间一行空气孔构成 W1 波导；在 W1 波导上耦合了 3 个微谐振腔，可以产生 3 个互不干扰的谐振峰。仿真结果表明，当微腔附近的折射率发生微小变化的时候，3 个谐振峰会依次产生线性偏移，并且互不干扰。3 个微谐振腔的 Q 值分别达
3、到了2672.413、2818.182、2460.317。最后，本文对不同葡萄糖浓度条件下尿样品进行了仿真，发现每一个尿样葡萄糖浓度值都可以对应一个独一无二的谐振波长，从而实现了该传感模型对尿糖浓度的检测。关键词：关键词：光子晶体 谐振腔 波导 传感 多路复用The design of micro-nano optical on-chip sensing model for future medical detection equipment in homeABSTRACTThe raise of live quality and the enhancement of public healt
4、h awareness have contributed to fast development of healthcare industry. As a sunrise industry, home medical industry meets the demands of market and therefore has board prospects in the future. Home medical equipment can help people monitor their health status in daily life and further adjust their
5、 lifestyle or get timely treatment, which makes it promising to be peoples first health defense line and improve overall health level. Traditional medical detecting methods are not suitable for home-use due to their complexity, high cost and low efficiency. In contrast, photonic crystal biosensor ha
6、s multiple advantages such as rapid, accurate, label-free and sensitive detection, and thus it applies well to future home medical equipment.In this paper, the theory knowledge and the sensing principle of photonic crystal have been introduced. Internal and overseas research actuality has been brief
7、ly summarized. By using the simulation tools like Rsoft and Lumerical, perfect photonic crystal, W1 waveguide, L3 micro-cavity and a larger defect hole structures properties are discussed. And on this basis, we present a novel paradigm. It is structured in a silicon slab(n=3.48) by arranging a trian
8、gular lattice, hole-array of air holes, where the central row of air holes is removed in order to form a line defect waveguide(W1) along which light can be guided. Two resonant micro-cavities, created by modifying the radius of a hole adjacent to the defect line, are coupled to the waveguide. Meanwh
9、ile, a declining L3 cavity is coupled to the waveguide as well. The transmission spectrum shows that three mutually independent resonance peaks would be observed. A slight change in the refractive index of the near field region surrounding the resonant cavity results in a shift in the resonant wavel
10、ength. The quality factors(Q) of these three cavities have reached 2672.413,2818.182 and 2460.317. From the simulation results, the change in the resonant wavelength has been observed with the change in the concentration of glucose in urine and thus by capturing these changes the concentration of gl
11、ucose in urine can be detected. KEY WORDS: photonic crystals resonance cavity waveguide sensors multipleI目目 录录第一章 绪论 .11.1 未来家用医疗检测设备需求分析.11.2 光子晶体传感器运用于未来家用医疗检测的优势分析.11.3 本文安排.2第二章 光子晶体基础知识 .42.1 光子晶体概述.42.2 光子晶体基础理论简介.42.3 光子晶体数值分析方法.52.3.1 平面波展开法.52.3.2 传输矩阵法.62.3.3 有限时域差分法.62.4 光子晶体数值仿真软件.62.5 光子晶体应用前景展望.7第三章 光子晶体生物传感器 .83.1 光子晶体传感器用于医疗检测的传感原理.83.2 光子晶体生物传感器用于检测生化指标的关键性能指标 .83.2.1 灵敏度 S.83.2.2 品质因子 Q.83.2.3 检测极限.
