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1、# #?i?kWhMFJo-1F81吴秀琳1,郭 华2,张 巧3,钱桂生3,方勇飞4(1.哈尔滨医科大学研究生学院 150081;2.重庆武警总队医院呼吸科 400061;3.第三军医大学新桥医院呼吸内科,重庆400037;4.第三军医大学西南医院中医科,重庆400038)K 1: 通过研究多发性肌炎(PM)和皮肌炎(DM)合并肺间质病变(ILD)患者的临床特点及其与抗Jo-1抗体的关系,探讨如何减少误诊和漏诊bZE 回顾性对比分析抗Jo-1抗体阳性36例和阴性118例PM/DM 患者,比较两组首发症状a临床及免疫学特征bT 抗Jo-1抗体阳性组以呼吸道症状首发者明显高于阴性组(52.8% v
2、s 3.4%,P 0.05)b1. 2 d9) FJo-1F8TsF36|F118,$s1F5+,SPSS12.0d9qsb9V 2_,P 0.05);7Ay0_q18(50%)#9(8%),FSSA/SSBF8sY18(50%)#19(16%),FRo-52sY18(50%)#9(8%),d9)F1sd9il( P 0.05),nV3bV2 FJo-1FFJo-1|F5+1 n(%)FYn ILDk14mvC?F36 23(63.9)* 29(80.6)* 27(75.0)* 6(16.7) 6(16.7) 8(22.2) 28(77.8)*|F118 8(6.8) 19(16.1) 28(
3、23.7) 19(16.1) 9(7.6) 28(23.7) 33(28.0) * :P 0.05,FJo-1F8|F1bV3 FJo-1FFJo-1|FLif_1n(%)FYn ANAFSSA/SSBFds-DNAFSmF8FRNPF8FRo-52 RFF36 18(50) 18(50)* 2(5.6) 2(5.6) 6(16.7) 18(50)* 18(50)*|F118 52(44) 19(16) 2(1.7) 2(1.7) 0(0) 9(8) 9(8) * :P 0.05,FJo-1F8|F1b3 ) 1980MNishikainQVPMb_B+s1&F8) )FJo-1F8bTagg
4、art3VPM/DMiILDFJo-1F8qVr50%75%,#FJo-1F8$?ILDS:F81bAUPM/DMiILDFJo-1F8qr25.8%,S3 ,S=x4-6Bb,FJo-1F8PM/DMiILDM1,FJo-1F8PM/DM,ILD?3qVr66%73.3%7-8bFAUFJo-1iILD63.9%,gLFJo-1F8PM/DMiILDMM1baa1(VPM/DMn?bAUFJo-1F8Fn?|F(52.8% vs 3.4%, P 0.05),Cottin9-12TBbFJo-1Fik(80.6%)a1(75%)a?(77.8%)q,|F1sd9il(P 0.05),f,13M
5、bDPM/DMYaM-ahyILD?3M1,71a1e$ILDM19bFJo-1F81?3qVr50% 100%1,12-13bFgAUFJo-1F8127,75%,B,O1n?r33.3%bFJo-1F8FRFqr50%,A|F(8%),sd9il( P 0.05)b#1n?RF$A1(RA)7,#jbfr14FRo-52FJo-1F8M1,gLFJo-1F8FFRo-52_qr50%,A|F(50% vs 8%, P 0. 05)bFAUFJo-1F8FFSSA/SSBF8_qA|F(50% vs16%, P 0.05)b8,FJo-1F8PM/DMiILDMM1,n?11.1%,7n?r
6、52.8%,1n?r33.3%,O1*C,HWKVr2 5M,PM/DM?hbFJo-1F8Fka1a?,RFq(),+?kW8aA1aA1i?ksb7FJo-1F8FRo-52aFSSA/SSBM1,_qb#5VCykWhM1hM,i_FJo-1F8FF8a,iPM/DM,EaPbFPM/DMiILD 31(20.12%)6(3.9%)i4AU#,$,BInkW%hak,;F%hi?kWhMV?,#FN%h5Mb8(5.2%);U,g4VC,CT#k?_4UkWhMbFithiLundberg159?C18%PM/DMsOqCT#k?T4Uks,5CU#4byN,PM/DM?B5ks,ypP
7、M/DM?sOqCT#k?_10,*iILD,L*#f4,43iqbID:1 Hirakata M,NagaiS.Interstitial lung disease in polymyo-sitisand dermatomyositisJ.Curr Opin(/1903:)1900 重庆医学2011年7月第40卷第19期+)b(3)l,9Fh?bID:1,$.*sZTsJ.W:D,2003,24(12):1349-1351.2 Jablensky A.Epidemiology of schizophrenia:the global bur-denof disease and disabilit
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