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1、Chinese Journal of Clinical Medicine,2010. Vol.17,No.6null null null S 5 D null 2010 M 12 null 17 null 6 nullnull null null null Z g u 2002M 2008M ? 3 i s 曹海滨1 null 黄继英1 null 时宝忆1 null 高虹2 null 余勇夫3( 1. 复旦大学附属中山医院青浦分院消化科,上海null 201700;2. 复旦大学附属中山医院消化科,上海null 200032; 3. 复旦大学公共卫生学院卫生统计教研室,上海null 20003
2、2)K 1 null 目的:分析上海市青浦区胃癌患者发病及生存情况,为今后的筛查和干预工作提供依据b方法:对上海市青浦区 2002年 2008年新发的原发性胃癌患者随访资料进行分析,描述发病年龄a性别a部位等特点,并建立Cox 比例风险模型,分析生存率的主要影响因素b结果:2002年 2008年上海市青浦区新发的原发性胃癌1 333例b发病年龄构成呈偏态分布,40岁以上发病率明显升高,发病高峰70 80岁;男性多于女性(2.14: 1) ;发病部位以胃体和胃窦最多见b1 333例胃癌患者中位生存时间为11.66个月,胃癌患者的1年生存率为49. 75%,5年生存率为23.67%b患者的死亡危险
3、按照部位依次(由低到高)为胃体a胃窦a胃底贲门a跨越部位a胃未特指b年龄越高,死亡危险越高,性别因素对生存率的影响无统计学意义b结论:上海市青浦区居民40岁以后胃癌的发病率明显上升,发病部位以胃体和胃窦为主, 1年生存率约 50%b1 o M null 原发性胃癌; null 生存率; null 生存分析 m s | null R735. 2null null D S M null AIncidenceandSurvival Analysison FollownullupDataof Gastric Cancer inQingpuDistrict of Shanghai null CAOHai
4、bin1 null HUANG Jiying1 null SHI Baoyi1 null GAO Hong2 null YU Yongfu3 null 1. Department of DigestiveDisease, ZhongshanHospital Qingpu Branch, Fudan University, Shanghai 201700,China; 2. Departnullmentof DigestiveDisease, ZhongshanHospital, FudanUniversity,Shanghai 200032, China; 3.Departnullmentof
5、 Biostatistics, Schoolof Public Health, Fudan University Shanghai 200032, ChinaAbstractnull Objective:To investigate the incidence and survival rates on follownullup data about gastric cancer patients in Qingpudistrict in Shanghai.Methods:The follownullup data of new gastric cancer cases between 200
6、2null2008 in Qingpu district was investinullgated. Data about age at diagnosis, gender, survival time, cancer site were collected. Stata 8. 0 software was used to analyze.Survival rate was analyzed with single and multiple Cox proportional hazards regression model respectively.Results: T he data of1
7、 333 gastric cancer cases were analysed. The incidence increased since 40 years old and the peak was at 70null80 ys. The ratio ofmale versus female was 2.14! 1. Gastric corpus and pylori were the most common sites of gastric cancer. T he median survivaltime was 11. 66 months. One year survival rate
8、was 49. 75% and the five year survival rate was23. 67%. The hazard ratio ofdeath of patients with cancer at stomach corpus or pylori was lower than those with cancer at fundus, cardia or site unclear.Conclusions: The incidence increased after 40 years old in Qingpu district in Shanghai. Gastric corp
9、us and pylori were the comnullmon sites for gastric cancer. The one year survival rate was about 50%.KeyWordsnull Gastric cancer; null Survival rate; null Survival analysisY T null ,Enullmail:null null K n 0 ? B b W M h q 29. 34/10 , 0 ? 2 b S , M h q 23. 14/10 , 0 ? q 3 , 0 ? 23. 5% 1b Z g u ? h #
10、3i f , u 2002M 2008M ? ? 5 $ s , + M ? h a 3 i H W M 1 B y b1null Z E1. 1null 对象来源 null Z g u ! , 2002M 1 1 2008M 12 31 S : ? ? M 1 5 b g u s 4 b1. 2null 方法null Z g u % h e ? : d b S Z g u ! h b = a Y a 3 M aE V a ? a G b S = % h s826null S 5 D null 2010 M 12 null 17 null 6 null null Chinese Journal
11、 of Clinical Medicine, 2010.Vol.17,No. 6 ICDnull10 Cl6 ( 0 ? )b1. 3null 随访资料的有关定义null T 4 , T 4 ( ), H W 2002M 1 1 2009M 4 30 b H W K 6. 25 M b H W = C TY q ( j b4 H W V U ,M - aY (3 = 1,o = 0)T x M b1. 4null 统计学分析null Z g u % h e 2002 M 2008 M , p y o bd 9 s Stata 8. 0d 9 q bs Z E 3 i s b| C H W # H I n ; y s Lognullrank_ ; y 3 i s Cox 1 B 2 , d KaplannullMeier E 9 3i q , Lognullrank_ F 3 i q 1 , t_ F M - 1 bP 0. 05 s d 9 il b2null null null T2. 1null 原发性胃癌患者的发病情况null 2002M 2008M Z g u ? h 1 333 (V 1),?h q 41. 65/ 10 b
