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1、1Analysis of the pharmacological effects of SolidagoAbstract: The purpose of a flowers chemical composition, pharmacological effects and clinical applications are reviewed for further study based on providing work Solidago Methods access to the relevant literature, analyzed and summarized. Solidago
2、mainly contains the results of flavonoids, saponins, benzyl benzoate, cinnamic acid ester Angelica, an acetylene compound, styrene-acrylic acid; has antibacterial, diuretic, expectorant asthma and blood pressure, gastric mucosal protection and promotion of intestinal smooth muscle of the movement ph
3、armacological activity; a wide range of clinical applications Conclusions Solidago has a value of further research and application. Keywords: Solidago pharmacological effects of ingredients 0 Introduction Department of Asteraceae Solidago Solidago genus of a species, mainly located in Chinas East, S
4、outh, Southwest and Shaanxi and Taiwan, its growth in different different different 2names, such as wild Huang (), hillsides and a half sticks of incense, sprinkling Golden Flower (), Asarum yellow, yellow Yi Zhixiang (), a fragrant yellow () Solidago as a medicine, is widely used in Chinas civil so
5、ciety, with wind, detoxification function of swelling, mainly for the treatment of Fengreganmao, headache, sore throat, Hyperactivity cough, jaundice, vent diarrhea, hot shower, carbuncle swollen boils, snake bites and bruises, tulip style etc. modern pharmacology that Solidago has antibacterial, di
6、uretic, expectorant asthma and other effects, recent studies have also found a yellow blood pressure, gastric mucosal protection and promotion of intestinal smooth muscle function. 1 composition of Solidago Solidago species varieties, more than 120 species, is grown mainly in North America, of which
7、 China has four varieties: fruit a yellow hair, a flower, a flower bud blunt and Solidago 3canadensis. On the chemical composition of the genus Solidago research in Western European countries are more different species have differences of chemical composition, a yellow (mainly containing flavonoids,
8、 saponins, benzyl benzoate, cinnamon, angelica acid esters, acetylene is a compound, styrene-acrylic acid. 1.1 flavonoid rutin (Rutin), kaempferol -3- rutin glucosidase, different quercitrin, kaempferol - glucoside. 1.2 saponins Solidago phenolic glycosides (leiocarposide). 1.3 benzyl ester 2,3,6 -
9、trimethoxy benzoic acid - (2 - methoxy-benzyl) ester, 2,6 - dimethoxy-benzoic acid - (2 - methoxy-benzyl) ester , 2 - hydroxy-6 - methoxy benzyl benzoate, 2,6 - dimethoxy-benzyl benzoate. 1.4 Angelica Angelica acid esters of cinnamic acid, 3,5 - dimethoxy-4 - acetoxy cinnamic esters, angelica acid -
10、3- methoxy-4 - acetoxy cinnamic ester. 1.5 acetylene compound is (2E-8Z) - Kuei - diene-4 ,6 - diyne ester, (2Z-8Z) - Kuei - diene-4 ,6 - diyne ester. 1.6 acrylic acid caffeic acid (Caffeic acid), 4chlorogenic acid (Chlorogenicacid). 1.7 Other sitosterol (sitosterol) 5, -juniper posts ene (-cadinene
11、), and a variety of trace elements, including Ca2 +, Mg2 + content more. Pharmacological activity of Solidago 2 Solidago Solidago decurrens on the pharmacological activity of research, have not been reported abroad, foreign fruit of the same genus Solidago hair more in-depth study, reported more pha
12、rmacological activity of anti-inflammatory, antibacterial, diuretic, anti-tumor activity and so on in China, pharmacological activity of Solidago early studies reported in the following record: 2.1 decoction antibacterial activity against Staphylococcus aureus, Salmonella typhi have varying degrees
13、of inhibition of red rubrum and Trichophyton birds have a strong bactericidal effect. Solidago decoction has anti-alcohol extract of Candida albicans, the considerable efficacy and nystatin. 2.2 expectorant effects asthma bronchitis in rabbits (inhalation of ammonia vapor extraction), Oral decoction
14、, can relieve wheezing, have expectorant effect. 52.3 Other experiments show that animals can promote the role of leukocyte phagocytosis. Acute (hemorrhagic) nephritis hemostatic effect, in mice injected with extracts of the diuretic effect, but large doses of anti-can reduce urine output. Recent st
15、udies have also found the following pharmacological activities: 2.4 antihypertensive effect of a yellow decoction can significantly reduce blood pressure in anesthetized rabbits, inhibition of toad cardiac contractility, reduced heart rate and cardiac output toad, the blood pressure amplitude and du
16、ration of blood pressure with isoproterenol quite. 2.5 gastric mucosal protective effect of indomethacin prior to intraperitoneal injection of a yellow decoction 2h, 6h after the animals were killed, discovery and control group, the ulcer score was significantly lower than the control group. Links to free download http
