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1、The The MovementMovement Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Tel 1 414 276 2145 www MovementDisorders org Info info movementdisorders orgTel 1 414 276 2145 www MovementDisord
2、ers org Info info movementdisorders org PARKINSONISMPARKINSONISM Kathleen M Shannon M D Kathleen M Shannon M D Parkinsonism Kathleen M Shannon M D The The MovementMovement Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Disorder Society 555 East Wells Street Suite 11
3、00 Milwaukee Wisconsin 53202 3823 Tel 1 414 276 2145 www MovementDisorders org Info info movementdisorders orgTel 1 414 276 2145 www MovementDisorders org Info info movementdisorders org PARKINSONISMPARKINSONISM Kathleen M Shannon M D Kathleen M Shannon M D Parkinsonism Cardinal features Tremor Rest
4、 Postural Bradykinesia Rigidity Postural reflex impairment Need 2 3 The The MovementMovement Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Tel 1 414 276 2145 www MovementDisorders org
5、Info info movementdisorders orgTel 1 414 276 2145 www MovementDisorders org Info info movementdisorders org PARKINSONISMPARKINSONISM Kathleen M Shannon M D Kathleen M Shannon M D Degenerative Parkinsonisms Parkinson s disease Hereditary forms Sporadic Multiple system atrophy MSA Diffuse Lewy body di
6、sease Progressive supranuclear palsy PSP Corticobasal degeneration Frontotemporal dementia with parkinsonism Pallidal degenerations Alzheimer disease Spinocerebellar ataxias types 2 3 17 The The MovementMovement Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Disorde
7、r Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Tel 1 414 276 2145 www MovementDisorders org Info info movementdisorders orgTel 1 414 276 2145 www MovementDisorders org Info info movementdisorders org PARKINSONISMPARKINSONISM Kathleen M Shannon M D Kathleen M Shannon M D De
8、generative Parkinsonisms Huntington s disease Juvenile presentation Later in disease course Wilson disease Acquired hepatolenticular degeneration Parkinsonism Dementia Complex of Guam Neuroferritinopathy Basal Ganglia calcification Gaucher s disease GM1 gangliosidosis Chediak Higashi disease Chorea
9、acanthocytosis The The MovementMovement Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Disorder Society 555 East Wells Street Suite 1100 Milwaukee Wisconsin 53202 3823 Tel 1 414 276 2145 www MovementDisorders org Info info movementdisorders orgTel 1 414 276 2145 www
10、 MovementDisorders org Info info movementdisorders org PARKINSONISMPARKINSONISM Kathleen M Shannon M D Kathleen M Shannon M D Secondary Parkinsonisms Post encephalitic Post traumatic Vascular Hydrocephalus Space occupying lesion Toxic Manganese MPTP Carbon monoxide Cyanide Carbon disulfide Drug induced DA receptor blockers Antipsychotics Anti emetics CA channel blockers Anticonvulsants Phenytoin Valproic acid Antiarrhythmics Amiodarone Others Lithium