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1、气候带划分Classfication of Climatic zones (I) 药物稳定性长期试验所采用的一般条件是根据国际气候带制定的。将全球分为I、II、III、IV四个国际气候带，即温带、亚热带、干热带和湿热带。该划分由W. Grimm应用平均热力学温度为基础制订。具体见下表。The world has been divided into four climate zones with countries being assigned to the relevant zones. This is largely the work of W. Grimm (Grimm, 1985) wh
2、o used the mean kinetic temperature (MKT) as the basis. The four zones are described in figure.气候带Designation 计算数据Calculated data推算数据Evaluated data温度Temperature平均热力学温度MKT湿度Humidity温度Temperature湿度HumidityI 温带Moderate20.020.042%2145%II 地中海气候，亚热带Subtropical21.622.052%2560%III 干热带Hot (dry)26.427.935%302
3、5%IV 湿热带Tropical 26.727.476%3070% As this classification demonstrates, approximately 90% of the global pharmaceutical market lies in the moderate (I) or subtropical (II) climate zones. 按此划分，全球约90%的药品市场位于气候带I（温带）或气候带II（亚热带）。W. Grimm研究列出的国家见下表。Classification of some countries studied by W. Grimm list
4、as below. 根据气候带划分国家气候归类Classification of Countries According to Climatic Zones用于药物稳定性试验FOR DRUG STABILITY TESTINGSNCountry 国家Climatic Zones地处气候带Assigned To稳定性适用气候带1Afghanistan阿富汗I, II II2Algeria阿尔及利亚II, III II (a)3Angola安哥拉II, IV II4Argentina阿根廷II II5Armenia亚美尼亚I, II II (a)6Australia澳大利亚I, II, III,
5、IV II7Azerbaijan阿塞拜疆I, II II8Bahrain巴林IVIV9Bangladesh孟加拉国IV IV10Barbados巴巴多斯IV IV11Belize伯利兹IV IV12Benin贝宁IV IV13Bolivia玻利维亚I, II, IV II (a)14Botswana伯兹瓦纳III III 15Brazil 巴西II, IV IV16Bulgaria保加利亚I, IIII17Burkina Faso布基纳法索IVIV18Burundi布隆迪IVIV19Cameroon喀麦隆IVIV20Canada加拿大II21Canary Islands加那利群岛IIII22C
6、entral African Republic中非共和国IVIV23Chad乍得III, IVIII24Chile智利I, IIII25China中国I, II, IVII(a)26Columbia哥伦比亚IVIV27Congo刚果II, IVIV28Costa哥斯达黎加IVIV29Cuba古巴IVIV30Dominican Republic多米尼加共和国IVIV31Dutch Antilles荷属安地列斯群岛IVIV32Ecuador厄瓜多尔I, II, IIIIV33Egypt埃及II, IIIII(a)34El Salvador萨尔瓦多IVIV35Ethiopia埃塞俄比亚II, IVIV36Fiji斐济IVIV37France法国I, IIII38Gabon加蓬IVIV39Gambia冈比亚IVIV40Georgia格鲁吉亚I, IIII41Germany德国II42Ghana加纳IVIV43Greece希腊II, IVII44Guatemala危地马拉IVIV45Guinca几内亚IVIV46Guyana圭亚那IVIV47Haiti海地IVIV48Honduras洪都拉斯II, IVIV49Hong Kong香港IVIV50India印度III, IVIV3 / 3
