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1、氨基酸糖苷类（Amino acid glycosides）test questions(1) multiple-choice questionsType A problem1., about aminoglycoside antibiotics, the correct statement is thatA. is acidicB. chemical property is unstableC. oral absorptionD. is mainly excreted through the kidneysE. belongs to alkaloids2. drugs that are not
2、 aminoglycoside antibiotics are:A. NeomycinB. tobramycinC. sisomicinNetilmicin, D.Jos E.3. What kind of bacteria are ineffective for aminoglycoside antibiotics?A. anaerobic bacteriaPseudomonas aeruginosa B.C. tubercle bacillusD. Gram-negative bacteriaE. Gram-positive bacteria4. aminoglycoside antibi
3、otics are mainly distributed in:A. CSFB. serosa cavityC. plasmaD. intracellular fluidE. extracellular fluidThe incidence of anaphylactic shock in 5. aminoglycosides is the highest:A. gentamicinB. streptomycinC. NeomycinD. kanamycinE. tobramycinThe highest incidence of vestibular function damage in 6
4、. aminoglycosides is:A. kanamycinB. streptomycinC. NeomycinD. sisomicinE. tobramycinThe highest incidence of cochlear nerve injury in 7. aminoglycosides is:A. kanamycinB. streptomycinC. NeomycinD. sisomicinE. tobramycin8. streptomycin and furosemide combination will cause:A. nephrotoxicity increased
5、B.Ototoxicity increaseC. increased antimicrobial activityD. increased diuresisE. has no obvious effect9. plague and rabbit fever are the first treatment options:A. streptomycinB. gentamicinAmikacin, C.D. tobramycinE. Neomycin10. drugs that are ineffective against Pseudomonas aeruginosa are:A. gentam
6、icinB. tobramycinC. AmikacinD. sisomicinE. kanamycin11. drugs that are effective in treating tuberculosis are:A. gentamicinB. AmikacinC. kanamycinD. tobramycinNetilmicin, E.12., the description of gentamicin is correct:A. was ineffective against Pseudomonas aeruginosaB. should not be used in combina
7、tion with ampicillin and benzyl penicillinC. the concentration of the liquid in the urine is lowAntimicrobial spectrum of D. is the most widely used in aminoglycosidesE. can be used in the treatment of tuberculosis13., Amikacins role is characterized by:Antimicrobial spectrum of A. is the most widel
8、y used in aminoglycosidesB. is susceptible to drug resistanceC. was ineffective against Pseudomonas aeruginosaD. is highly toxicE. can be used in the treatment of tuberculosis14. bacterial resistance to aminoglycosides is due to production:A. hydrolaseB. peptidaseC.b- lactamaseD. inactivation enzyme
9、E. synthetase15. the following description is wrong to tobramycin:A. is made by deoxygenation of kanamycin BB. has a strong effect on Pseudomonas aeruginosaC.Can be used for the treatment of tuberculosisD. has antimicrobial activity even when resistant strains of Pseudomonas aeruginosa are producedE
10、. can be used for the infection of Pseudomonas aeruginosa16. neomycin for clinical use:A. is used for Pseudomonas aeruginosa infectionB. is used for intestinal infection or abdominal preoperative disinfectionTreatment of urinary system infection with C.Treatment of lobar pneumonia with D.E. treatmen
11、t of tuberculosisThe mechanism of action of 17. aminoglycoside antibiotics is:A. prevents bacterial cell wall synthesisB. inhibits dihydrofolate synthetaseC. increases the permeability of the cell membraneD. inhibits DNA helicaseE. blocks the synthesis of bacterial proteins18. and the combination is
12、 prone to respiratory paralysis curare:A. penicillinB. streptomycinC. erythromycinD. sulfadiazineE. tetracyclineType B problemA. streptomycin, B. neomycin, C. spectinomycin, D., Amikacin, E., kanamycin19. drugs that are ineffective against Pseudomonas aeruginosa are20. 、 the commonly used medicine f
13、or tuberculosis is21. because of its high toxicity, it is forbidden to take intravenous injection22. clinical only for the treatment of uncomplicated gonorrhea isA. B. Amikacin C. D. streptomycin gentamicin kanamycin tobramycin E.23. the first remedy for plague is24., the treatment of gram-negative
14、bacilli infection, such as sepsis, is the preferred drugAmong the 25. aminoglycoside antibiotics, the most widely used are antibiotics26. of the most powerful drugs against Pseudomonas aeruginosa areType X problemTwenty-sevenBacterial resistance to aminoglycosides is the cause of resistance:A. produces hydrolasesB. produces inactive enzymesAlterations in cell wall permeability of C. bacteriaD. bacteria lack autolysis enzymesAbnormalities in intracellular transport function of E. bacteria28. aminoglycoside antibiotics affect the synthesis of proteins, including
