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1、H4AocPRMChang-ilParkM.D.Ph.D,.DepartmentandResearchInstituteofRehabilitationMedicineYonseiUniversityCollegeofMedicine,SeoulKorea膏MRIEvaluationHighlysensitivetodetectgrossstracturalabnorttalitiesinCP譬eriventricu_arLeukomalaciainMRI。Leadingcauseofchronicmotordisability。Damageoftheimmaturecerebralwhite
2、matter,occuringintheperinatalperiod(commonlyoccuringbetween24to34weeks)AOcPRM纂PathologyofPVL。FocalnecrosisintheperiventricularregionDiffusereactivegliosisinthesurroundingWhitematterAOcPRM喜MajorInteractingFactorsofPVTL。Incompletedevelopmentofthevascularsupplytothecerebralhitematter。Maturation-depende
3、ntimpairiaeiit训regulationofcerebralbloodflowAOcPRM暮Questions?1.IsPVLtheetiologicfactorinthepathogenesisofspastictypeofCP?2.Isthelaznage0fthecorticospinaltracteausedbyPVL23.IsthespasticityandmotordysfunctionofCPcausedbydamagedcorticospinaltract?AOcPRMBrainMRIandSPECTFindings嘉inChildrenwithCerebralPal
4、sy。Purpose:TocompareBrainMRIandSPECTfindingsinchildrenwithcerebralpalsy_Subject:60childrenwithcerebralpalsyDSpastiediplegia:44pts2)Spasticqudriplegia:11pts3)Spastichemiplegia:2pts4)Athetoidtype:3pts咤Parkefa(1997,JKoreendcadRehiabi7Med)fhocpRM纂BrainSPECTFindingsinCerebralPalsy“Hypoperfusioninbilatera
5、lthalamus7山T55人阮tfeAocpRMBrainMRI&SPECTFindingsinCPspasticdiplegiaBrainMRI:LossofperiventricularwhitematterBrainSPECT:MarkedlydecreasedperfusioninbilateralthalamusAOcPRMBrainMRI&SPECTFindings嘉inCPAthetoidTypeBrainSPECT:severelydecreasedpertusioninbilateralthalamus&leftbasalgangliaBrainMRI:normalfeAocpRM