《部分纳米材料的纳米生物学效应研究》由会员分享，可在线阅读，更多相关《部分纳米材料的纳米生物学效应研究（5页珍藏版）》请在金锄头文库上搜索。
1、2006Mnull 726null7$D5Basic & C lin ica lM edicineJuly 2006Vo.l 26null No. 7l: 2006- 04- 12:SE1S( 10490180) ;SEM( 10525524);SZ_( K JCXnullSWnullH 12)*YT( corresponding author): zhaoyuliang ihep. ac. cncI|: 1 001null6 32 5( 2 006 ) 0 7null0 69 9null0558nulls,3r孟null 幻1, 3, 陈null 真1, 3, 赵宇亮1, 2, 3*( 1n
2、ullSS?,3rLi,100049; 2nullSE,3rLi,100080; 3nullSS3,100049)K1:9M,3()rZZbe,j/+y#38MTV?3Y,|1)s,38a%3,3()rbK|,3r_,hZBtTbH,3()r5Bt-Z_,)b1oM:,;,;3r;r;,ms|: R 318null 08null nullDSM: AB iolog ical effects of som e nanom ateria lsMENG H uan1, 3, CH EN Zhen1, 3, ZHAO Yunullliang1, 2, 3*( 1nullLab for B ionull
3、Env ironm en talH ealth Sciences of NanoscaleM aterials, Institu te ofH igh Energy Physics, Ch inese Acad emy of Sciences,Beijing, 100039; 2nullN ation alC enter for Nanoscience and Nanotechnology, B eijing, 100080; 3nullC ollege of Ch em istry, G raduate Un iversityof Ch in ese Academ y of Sciences
4、, Beijing 100039, C hina)Abstract: W e briefly summ arize the current understand ing on the biological activ ities of som e m anufactured nanonullm ateria ls ( S ing le wa ll carbon nanotubes, M u ltiw all carbon nanotubes, H ydroxy lated carbon nano tubes, C60 nullFu llerene, H ydroxy lated C60, Gd
5、nullm etallofu llerenols, Nanosized copper partic les, N anosized zinc partic les andnanosized titan ium ox ide partic les, etc) and their healthy effects. F inally, the w ays to elim inate or reduce thenanotox ic ity o f nanosca le m aterials and the reverse utilization ( in m ed ical fie lds) of t
6、he nano tox ico log ica l effects arebr ie fly argued.Key words: nanotox icity; nanonullsize effect; nanonullstruc ture effects; hea lthy e ffect1null,/1 100 nm/FaTa/,20W/?ZATb,S/1$B/,b,/ 5000 m g /kgbH odge and Sterner Sca lesE,7bh_?C,?l/aa3A,Ha/?M13Ssb,V?Q8=3Q)0 11b( 58 null 16) nm,( 1null08 null
7、0null25) nullm,g$,?CK4( 5 g /kg)H,V(q10% ),iCQ,bL?C_aaa%?aUSA6bhLT9C/lonhMb9,CtsVC,1M4,RsQ 12b2null2null%,3()r8%!LV,RV%a%?a|.ea|3YbavV 13C,5HEK293%Y,?CC,5P%sVT=G1,%,%*?,iCnull4nullrnull1bYV3W estern B lo t:M?C,C,5VY%yVr,i%*1VrbC603VhN nullJnullDnull?(NMDA )37*%,FC60 ( C( COOH ) 2 ) 3s8C3D37, C3z7002
8、006null26( 7)$D5null null Basic& C lin ica lM edic ine 14b,R%,7O?&?% 15bC,5aC,58k%(H,t,R%?a%(3vYb6,i3null06 nullg /cm3C,5C,5%ia%la%llMC,V?%1bM4/,%/:C,5C,5F(v) C60 16 b,R3r,VB,+sbFM,3,3()r,vGib3null,3()r_,h3null1null,3r_,3r,D,0$b,R Gd C82 ( OH ) 22 nF?3?CBz0bKGd C82 ( OH ) xzE|7?H/4,LP541 /33Gd C82 ( OH ) xV1C/4GdnullDTPAzrT 17 18bL9?C,Gd C82 ( OH ) x,L,R30 m in,M, MRI48=AE5bAP/47?45,!97?BAF?54bsTv,sY
